6IEG

Crystal structure of human MTR4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, A	Exosome RNA helicase MTR4	polymer	1002	114162.6	2	UniProt (P42285) Pfam (PF00270) Pfam (PF00271) Pfam (PF21408) Pfam (PF13234) Pfam (PF08148) In PDB	Homo sapiens (human)	ATP-dependent RNA helicase DOB1,ATP-dependent RNA helicase SKIV2L2,Superkiller viralicidic activity 2-like 2,TRAMP-like complex helicase
2	B, A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	B, A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

B, A: 71 - 1042 (UniProt: P42285)

PDB	External Database	Details
Met 41	-	initiating methionine
Ser 42	-	expression tag
Tyr 43	-	expression tag
Tyr 44	-	expression tag
His 45	-	expression tag
His 46	-	expression tag
His 47	-	expression tag
His 48	-	expression tag
His 49	-	expression tag
His 50	-	expression tag
Asp 51	-	expression tag
Tyr 52	-	expression tag
Asp 53	-	expression tag
Ile 54	-	expression tag
Pro 55	-	expression tag
Thr 56	-	expression tag
Thr 57	-	expression tag
Glu 58	-	expression tag
Asn 59	-	expression tag
Leu 60	-	expression tag
Tyr 61	-	expression tag
Phe 62	-	expression tag
Gln 63	-	expression tag
Gly 64	-	expression tag
Ala 65	-	expression tag
Met 66	-	expression tag
Asp 67	-	expression tag
Pro 68	-	expression tag
Glu 69	-	expression tag
Phe 70	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	228325.2
Non-Polymers*	Number of molecules	4
	Total formula weight	903.0
All*	Total formula weight	229228.2

*Water molecules are not included.