6IDE
Crystal structure of the Vibrio cholera VqmA-Ligand-DNA complex provides molecular mechanisms for drug design
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Transcriptional regulator LuxR family | polymer | 256 | 28868.1 | 2 | UniProt (A0A0H6WEL7) In PDB | Vibrio cholerae | |
2 | C | DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*AP*AP*TP*CP*CP*CP*CP*CP*CP*T)-3') | polymer | 18 | 5526.6 | 1 | Vibrio cholerae | ||
3 | D | DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*TP*TP*TP*CP*CP*CP*CP*CP*CP*T)-3') | polymer | 18 | 5508.6 | 1 | Vibrio cholerae | ||
4 | A, B | 3,5-dimethylpyrazin-2-ol | non-polymer | 124.1 | 2 | Chemie (A1U) | |||
5 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 246 (UniProt: A0A0H6WEL7)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Lys 1 | - | expression tag |
Leu 247 | - | expression tag |
Leu 248 | - | expression tag |
Glu 249 | - | expression tag |
His 250 | - | expression tag |
His 251 | - | expression tag |
His 252 | - | expression tag |
His 253 | - | expression tag |
His 254 | - | expression tag |
His 255 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 68771.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 248.3 | |
All* | Total formula weight | 69019.7 |