6I9M
JmjC domain-containing protein 5 (JMJD5) in complex with Mn and R-2-hydroxyglutarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | JmjC domain-containing protein 5 | polymer | 256 | 29733.5 | 1 | UniProt (Q8N371) Pfam (PF13621) | Homo sapiens (Human) | Jumonji domain-containing protein 5,Lysine-specific demethylase 8 |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | (2R)-2-hydroxypentanedioic acid | non-polymer | 148.1 | 1 | Chemie (2HG) | |||
| 4 | D (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | E, F, G (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | H (A) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A: 183 - 416 (UniProt: Q8N371)
| PDB | External Database | Details |
|---|---|---|
| Met 161 | - | initiating methionine |
| His 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| Ser 168 | - | expression tag |
| Ser 169 | - | expression tag |
| Gly 170 | - | expression tag |
| Val 171 | - | expression tag |
| Asp 172 | - | expression tag |
| Leu 173 | - | expression tag |
| Gly 174 | - | expression tag |
| Thr 175 | - | expression tag |
| Glu 176 | - | expression tag |
| Asn 177 | - | expression tag |
| Leu 178 | - | expression tag |
| Tyr 179 | - | expression tag |
| Phe 180 | - | expression tag |
| Gln 181 | - | expression tag |
| Ser 182 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29733.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 601.5 | |
| All* | Total formula weight | 30335.0 |
