6I8Z
Crystal structure of PTK2 in complex with BI-4464.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Focal adhesion kinase 1 | polymer | 281 | 32247.2 | 1 | UniProt (Q05397) Pfam (PF07714) In PDB | Homo sapiens (Human) | FADK 1,Focal adhesion kinase-related nonkinase,FRNK,Protein phosphatase 1 regulatory subunit 71,PPP1R71,Protein-tyrosine kinase 2,p125FAK,pp125FAK |
| 2 | A | 3-methoxy-~{N}-(1-methylpiperidin-1-ium-4-yl)-4-[[4-[(3-oxidanylidene-1,2-dihydroinden-4-yl)oxy]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide | non-polymer | 556.6 | 1 | Chemie (H82) | |||
| 3 | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A: 411 - 689 (UniProt: Q05397)
| PDB | External Database | Details |
|---|---|---|
| Gly 409 | - | expression tag |
| Ser 410 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32247.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 556.6 | |
| All* | Total formula weight | 32803.7 |
