6I7S

Microsomal triglyceride transfer protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein disulfide-isomerase	polymer	492	55496.0	2	UniProt (P07237) Pfam (PF00085) Pfam (PF13848)	Homo sapiens (Human)	PDI,Cellular thyroid hormone-binding protein,Prolyl 4-hydroxylase subunit beta,p55
2	C, D (G, H)	Microsomal triglyceride transfer protein large subunit	polymer	884	98605.0	2	UniProt (P55157) Pfam (PF01347) Pfam (PF19444)	Homo sapiens (Human)
3	E, K (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	DA, EA, F, FA, G... (G, A, B, H)	1,2-ETHANEDIOL	non-polymer		62.1	19	Chemie (EDO)
5	L, M, NA, OA, PA... (B, H, G)	TRIETHYLENE GLYCOL	non-polymer		150.2	6	Chemie (PGE)
6	AA, BA, CA, N, QA... (G, B, H)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
7	AB, BB, CB, JA, KA... (H, G, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	9	Chemie (PEG)
8	LA, T (H, G)	3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL	non-polymer		398.5	2	Chemie (PE5)
9	V (G)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
10	MA (H)	2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		354.4	1	Chemie (PE4)
11	DB, EB, FB, GB (A, B, G, H)	water	water		18.0	222	Chemie (HOH)

Sequence modifications

A, B: 18 - 508 (UniProt: P07237)

PDB	External Database	Details
Met 17	-	initiating methionine

G, H: 19 - 894 (UniProt: P55157)

PDB	External Database	Details
Met 11	-	initiating methionine
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
Met 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	308201.9
Non-Polymers*	Number of molecules	51
	Total formula weight	5445.8
All*	Total formula weight	313647.7

*Water molecules are not included.