6I7P

Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	NS5	polymer	914	104329.9	6	UniProt (A0A1B2ZC85) Pfam (PF01728) Pfam (PF00972) Pfam (PF20483) UniProt (by SIFTS) (A0A024B7W1)	Zika virus (ZIKV)
2	AA, FA, G, L, P... (E, F, A, B, C...)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	6	Chemie (SAH)
3	BA, CA, GA, H, HA... (E, F, A, B, C...)	PHOSPHATE ION	non-polymer		95.0	15	Chemie (PO4)
4	DA, EA, J, K, KA... (E, A, F, B, C...)	ZINC ION	non-polymer		65.4	11	Chemie (ZN)

Sequence modifications

A, B, C, D, E, F: 1 - 903 (UniProt: A0A1B2ZC85)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 904	-	expression tag
Ser 905	-	expression tag
Ser 906	-	expression tag
Ser 907	-	expression tag
His 908	-	expression tag
His 909	-	expression tag
His 910	-	expression tag
His 911	-	expression tag
His 912	-	expression tag
His 913	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	625979.5
Non-Polymers*	Number of molecules	32
	Total formula weight	4450.5
All*	Total formula weight	630430.1

*Water molecules are not included.