6I79
SEPIAPTERIN REDUCTASE IN COMPLEX WITH COMPOUND 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Sepiapterin reductase | polymer | 276 | 29948.5 | 2 | UniProt (P35270) Pfam (PF00106) | Homo sapiens (Human) | SPR |
| 2 | C, E (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 3 | D, F (A, B) | 6-[(4-~{tert}-butyl-1,3-thiazol-2-yl)methyl]-4,6-diazaspiro[2.4]heptane-5,7-dione | non-polymer | 279.4 | 2 | Chemie (H5E) PubChem (75517293) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 261 (UniProt: P35270)
| PDB | External Database | Details |
|---|---|---|
| Met -14 | - | initiating methionine |
| Gly -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59896.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2045.5 | |
| All* | Total formula weight | 61942.5 |
