6I5D

Crystal structure of an OXA-48 beta-lactamase synthetic mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Beta-lactamase	polymer	255	29769.7	2	UniProt (Q6XEC0) Pfam (PF00905)	Klebsiella pneumoniae
2	AA, BA, C, CA, D... (B, A)	GLYCEROL	non-polymer		92.1	13	Chemie (GOL)
3	F (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	EA, G, H, I, J... (B, A)	NITRATE ION	non-polymer		62.0	6	Chemie (NO3)
5	FA, GA, HA, L, M... (B, A)	1,2-ETHANEDIOL	non-polymer		62.1	10	Chemie (EDO)
6	S (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
7	T (B)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
8	IA, JA (A, B)	water	water		18.0	376	Chemie (HOH)

Sequence modifications

A, B: 21 - 264 (UniProt: Q6XEC0)

PDB	External Database	Details
Met 20	-	initiating methionine
-	Pro 217	deletion
Phe 265	-	expression tag
Glu 266	-	expression tag
His 267	-	expression tag
His 268	-	expression tag
His 269	-	expression tag
His 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	59539.4
Non-Polymers*	Number of molecules	32
	Total formula weight	2426.5
All*	Total formula weight	61965.8

*Water molecules are not included.