6I45
Crystal structure of I13V/I62V/V77I South African HIV-1 subtype C protease containing a D25A mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protease | polymer | 99 | 10708.8 | 1 | UniProt (Q50BW9) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | B (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 3 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | D (A) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: Q50BW9)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | conflict |
| Val 13 | Ile 13 | conflict |
| Ala 25 | Asp 25 | engineered mutation |
| Val 62 | Ile 62 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10708.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 129.1 | |
| All* | Total formula weight | 10837.9 |
