6I3Z
Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin in complex with its antigen
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Alpha-1-antitrypsin | polymer | 356 | 40018.2 | 1 | UniProt (P01009) Pfam (PF00079) | Homo sapiens (Human) | Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| 2 | B (B) | Alpha-1-antitrypsin | polymer | 41 | 4681.6 | 1 | UniProt (P01009) | Homo sapiens (Human) | Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1 |
| 3 | C (H) | Fab 2H2 heavy chain | polymer | 216 | 23129.9 | 1 | Mus musculus (house mouse) | ||
| 4 | D (L) | Fab 2H2 light chain | polymer | 214 | 23914.4 | 1 | Mus musculus (house mouse) | ||
| 5 | E, G (A, L) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | H, I, J, K (A, B, H, L) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 2 - 353 (UniProt: P01009)
| PDB | External Database | Details |
|---|---|---|
| Met -2 | - | initiating methionine |
| Arg -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 91744.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 142.0 | |
| All* | Total formula weight | 91886.2 |
