6I2R
Crystal structure of the SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), mutant R802A, in complex with GarA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Multifunctional 2-oxoglutarate metabolism enzyme | polymer | 868 | 97080.5 | 2 | UniProt (A0R2B1) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870) | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | 2-hydroxy-3-oxoadipate synthase,HOAS,2-oxoglutarate carboxy-lyase,2-oxoglutarate decarboxylase,Alpha-ketoglutarate decarboxylase,KGD,Alpha-ketoglutarate-glyoxylate carboligase |
| 2 | B, D (B, D) | Glycogen accumulation regulator GarA | polymer | 115 | 12112.3 | 2 | UniProt (A0QYG2) Pfam (PF00498) | Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) | |
| 3 | E, H (A, C) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
| 4 | F, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, J (A, C) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 454 | Chemie (HOH) |
Sequence modifications
A, C: 361 - 1227 (UniProt: A0R2B1)
B, D: 45 - 158 (UniProt: A0QYG2)
| PDB | External Database | Details |
|---|---|---|
| Gly 360 | - | expression tag |
| Ala 802 | Arg 802 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 44 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 218385.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 979.4 | |
| All* | Total formula weight | 219365.0 |
