6I2K
Structure of EV71 complexed with its receptor SCARB2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Polyprotein | polymer | 297 | 32755.8 | 1 | Pfam (PF22663) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 2 | B (B) | Polyprotein | polymer | 254 | 27784.2 | 1 | UniProt (D4QGA2) Pfam (PF00073) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 3 | C (C) | Polyprotein | polymer | 242 | 26540.3 | 1 | UniProt (D4QGA3) Pfam (PF00073) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 4 | D (D) | Polyprotein | polymer | 58 | 6380.9 | 1 | UniProt (Q6YLE3) Pfam (PF02226) UniProt (by SIFTS) (Q66479) | Enterovirus A71 | |
| 5 | E (E) | Lysosome membrane protein 2 | polymer | 416 | 47727.8 | 1 | UniProt (Q14108) Pfam (PF01130) | Homo sapiens (Human) | 85 kDa lysosomal membrane sialoglycoprotein,LGP85,CD36 antigen-like 2,Lysosome membrane protein II,LIMP II,Scavenger receptor class B member 2 |
| 6 | F (F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 7 | G, I (G, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 8 | H (H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | J (J) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1883.7 | 1 | In PDB GlyTouCan (G60230HH) | |||
| 10 | K (K) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G22768VO) | |||
| 11 | L (A) | 1-(2-aminopyridin-4-yl)-3-[(3S)-5-{4-[(E)-(ethoxyimino)methyl]phenoxy}-3-methylpentyl]imidazolidin-2-one | non-polymer | 425.5 | 1 | Chemie (906) | |||
| 12 | M, N (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
E: 28 - 432 (UniProt: Q14108)
| PDB | External Database | Details |
|---|---|---|
| Glu 25 | - | expression tag |
| Thr 26 | - | expression tag |
| Gly 27 | - | expression tag |
| Gly 433 | - | expression tag |
| Lys 434 | - | expression tag |
| His 435 | - | expression tag |
| His 436 | - | expression tag |
| His 437 | - | expression tag |
| His 438 | - | expression tag |
| His 439 | - | expression tag |
| His 440 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 141189.0 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4978.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 867.9 | |
| All* | Total formula weight | 147035.5 |
