6I0J

Crystal structure of human carbonic anhydrase I in complex with the 4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl sulfamate inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Carbonic anhydrase 1	polymer	261	28906.2	2	UniProt (P00915) Pfam (PF00194)	Homo sapiens (Human)	Carbonate dehydratase I,Carbonic anhydrase B,CAB,Carbonic anhydrase I,CA-I
2	C, I (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, E (A)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	F, G, J (A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	H, K (A, B)	[4-[[4-chloranyl-3-(trifluoromethyl)phenyl]carbamoylamino]phenyl] sulfamate	non-polymer		409.8	2	Chemie (GZE)
6	L, M (A, B)	water	water		18.0	581	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57812.4
Non-Polymers*	Number of molecules	9
	Total formula weight	1344.7
All*	Total formula weight	59157.1

*Water molecules are not included.