6HZV
HUMAN JAK3 IN COMPLEX WITH LASW959 PROTEIN IN COMPLEX WITH LIGAND
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tyrosine-protein kinase JAK3 | polymer | 285 | 32690.3 | 4 | UniProt (P52333) Pfam (PF07714) | Homo sapiens | Janus kinase 3,JAK-3,Leukocyte janus kinase,L-JAK |
| 2 | E, F, G, H (A, B, C, D) | 3-[7-(2-hydroxyethyl)-9-(oxan-4-yl)-8-oxidanylidene-purin-2-yl]imidazo[1,2-a]pyridine-6-carbonitrile | non-polymer | 405.4 | 4 | Chemie (GYW) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 815 - 1099 (UniProt: P52333)
| PDB | External Database | Details |
|---|---|---|
| Ser 1048 | Cys 1048 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 130761.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1621.6 | |
| All* | Total formula weight | 132382.8 |
