6HXR

Human PARP16 (ARTD15) IN COMPLEX WITH EB-47

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Mono [ADP-ribose] polymerase PARP16	polymer	298	33582.2	3	UniProt (Q8N5Y8) Pfam (PF18084) Pfam (PF00644)	Homo sapiens (Human)	ADP-ribosyltransferase diphtheria toxin-like 15,Poly [ADP-ribose] polymerase 16,PARP-16
2	D, E (A, B)	2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide	non-polymer		537.5	2	Chemie (UHB)

Sequence modifications

A, B, C: 5 - 279 (UniProt: Q8N5Y8)

PDB	External Database	Details
Met -18	-	initiating methionine
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Val -8	-	expression tag
Asp -7	-	expression tag
Leu -6	-	expression tag
Gly -5	-	expression tag
Thr -4	-	expression tag
Glu -3	-	expression tag
Asn -2	-	expression tag
Leu -1	-	expression tag
Tyr 0	-	expression tag
Phe 1	-	expression tag
Gln 2	-	expression tag
Ser 3	-	expression tag
Met 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	100746.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1075.1
All*	Total formula weight	101821.8

*Water molecules are not included.