6HXR

Human PARP16 (ARTD15) IN COMPLEX WITH EB-47

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity
B	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity
C	0003950	molecular_function	NAD+-protein poly-ADP-ribosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue UHB A 301

Chain	Residue
A	HIS152
A	LEU171
A	TYR182
A	ALA190
A	TYR193
A	GLY153
A	SER154
A	ASN158
A	SER161
A	ILE162
A	GLY166
A	LEU167
A	HIS168

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site_id	AC2
Number of Residues	11
Details	binding site for residue UHB B 301

Chain	Residue
B	HIS152
B	GLY153
B	SER154
B	SER161
B	ILE162
B	GLY166
B	LEU167
B	HIS168
B	TYR182
B	ALA190
B	TYR193

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING: BINDING => ECO:0000269|PubMed:22661712

Chain	Residue	Details
A	HIS152
A	TYR182
A	TYR254
B	HIS152
B	TYR182
B	TYR254
C	HIS152
C	TYR182
C	TYR254

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site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Nicotinamide-stacking aromate => ECO:0000269|PubMed:22661712

Chain	Residue	Details
A	TYR193
B	TYR193
C	TYR193

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site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: ADP-ribosyl aspartic acid => ECO:0000269|PubMed:25043379

Chain	Residue	Details
A	ASP37
B	ASP37
C	ASP37

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site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: ADP-ribosyl glutamic acid => ECO:0000269|PubMed:25043379

Chain	Residue	Details
A	GLU70
B	GLU70
C	GLU70

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site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: N6-(ADP-ribosyl)lysine => ECO:0000269|PubMed:25043379

Chain	Residue	Details
A	LYS110
A	LYS137
B	LYS110
B	LYS137
C	LYS110
C	LYS137

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