6HXM
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-citrate synthase | polymer | 270 | 30008.0 | 2 | UniProt (P53396) Pfam (PF00285) | Homo sapiens (Human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
| 2 | C, E (A, B) | COENZYME A | non-polymer | 767.5 | 2 | Chemie (COA) | |||
| 3 | D, F (A, B) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 438 | Chemie (HOH) |
Sequence modifications
A, B: 836 - 1101 (UniProt: P53396)
| PDB | External Database | Details |
|---|---|---|
| Gly 832 | - | expression tag |
| Ser 833 | - | expression tag |
| His 834 | - | expression tag |
| Met 835 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60016.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1913.3 | |
| All* | Total formula weight | 61929.3 |
