6HXL
Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH (space group P21)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ATP-citrate synthase | polymer | 270 | 30008.0 | 8 | UniProt (P53396) Pfam (PF00285) | Homo sapiens (Human) | ATP-citrate (pro-S-)-lyase,ACL,Citrate cleavage enzyme |
| 2 | I, K, N, P, S... (A, B, C, D, E...) | COENZYME A | non-polymer | 767.5 | 7 | Chemie (COA) | |||
| 3 | J, L, O, T, X (A, B, C, E, G) | CITRATE ANION | non-polymer | 189.1 | 5 | Chemie (FLC) | |||
| 4 | M, U (B, E) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | Q, R (D) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | V (F) | OXIDIZED COENZYME A | non-polymer | 783.5 | 1 | Chemie (CAO) | |||
| 7 | Z (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 8 | AA, BA, CA, DA, EA... (A, B, C, D, E...) | water | water | 18.0 | 1713 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 836 - 1101 (UniProt: P53396)
| PDB | External Database | Details |
|---|---|---|
| Gly 832 | - | expression tag |
| Ser 833 | - | expression tag |
| His 834 | - | expression tag |
| Met 835 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 240064.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 7568.2 | |
| All* | Total formula weight | 247632.4 |
