6HXF
Human STK10 bound to a maleimide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (B, A, C, D) | Serine/threonine-protein kinase 10 | polymer | 302 | 34538.5 | 4 | UniProt (O94804) Pfam (PF00069) | Homo sapiens (Human) | Lymphocyte-oriented kinase |
| 2 | E, J, L, N (B, A, C, D) | 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl)phenyl]amino]pyrrole-2,5-dione | non-polymer | 398.4 | 4 | Chemie (R70) | |||
| 3 | F, G, H, I, M... (B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | K (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | R, S, T, U (B, A, C, D) | water | water | 18.0 | 725 | Chemie (HOH) |
Sequence modifications
B, A, C, D: 18 - 317 (UniProt: O94804)
| PDB | External Database | Details |
|---|---|---|
| Ser 16 | - | expression tag |
| Met 17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 138154.2 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 2125.6 | |
| All* | Total formula weight | 140279.8 |
