6HUY
HmdII from Desulfurobacterium thermolithotrophum reconstitued with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein | polymer | 370 | 40994.0 | 2 | UniProt (F0S2B6) Pfam (PF22616) Pfam (PF03201) | Desulfurobacterium thermolithotrophum DSM 11699 | |
| 2 | B, D (B, D) | Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein | polymer | 370 | 41010.0 | 2 | UniProt (F0S2B6) Pfam (PF22616) Pfam (PF03201) | Desulfurobacterium thermolithotrophum DSM 11699 | |
| 3 | E, N (A, C) | iron-guanylyl pyridinol cofactor | non-polymer | 686.3 | 2 | Chemie (FE9) | |||
| 4 | F, R (A, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | G, M, Q, V (A, B, C, D) | 5,10-Methenyltetrahydrofolate | non-polymer | 456.4 | 4 | Chemie (GUE) | |||
| 6 | H, I, J, K, O... (B, C, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 9 | Chemie (DMS) | |||
| 7 | L (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 8 | W, X, Y, Z (A, B, C, D) | water | water | 18.0 | 609 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 357 (UniProt: F0S2B6)
B, D: 1 - 357 (UniProt: F0S2B6)
| PDB | External Database | Details |
|---|---|---|
| Lys 358 | - | expression tag |
| Leu 359 | - | expression tag |
| Ala 360 | - | expression tag |
| Ala 361 | - | expression tag |
| Ala 362 | - | expression tag |
| Leu 363 | - | expression tag |
| Glu 364 | - | expression tag |
| His 365 | - | expression tag |
| His 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 358 | - | expression tag |
| Leu 359 | - | expression tag |
| Ala 360 | - | expression tag |
| Ala 361 | - | expression tag |
| Ala 362 | - | expression tag |
| Leu 363 | - | expression tag |
| Glu 364 | - | expression tag |
| His 365 | - | expression tag |
| His 366 | - | expression tag |
| His 367 | - | expression tag |
| His 368 | - | expression tag |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164008.0 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4280.0 | |
| All* | Total formula weight | 168288.0 |
