6HTF
Crystal structure of human Btk SH2 domain bound to rF10 repebody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase BTK | polymer | 117 | 13248.8 | 1 | UniProt (Q06187) Pfam (PF00017) | Homo sapiens (Human) | Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase |
| 2 | B (B) | rF10 repebody | polymer | 274 | 31097.3 | 1 | synthetic construct | ||
| 3 | C, D (A, B) | water | water | 18.0 | 126 | Chemie (HOH) |
Sequence modifications
A: 271 - 383 (UniProt: Q06187)
| PDB | External Database | Details |
|---|---|---|
| Gly 267 | - | expression tag |
| Ala 268 | - | expression tag |
| Met 269 | - | expression tag |
| Gly 270 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44346.1 | |
| All* | Total formula weight | 44346.1 |
