6HT5
Oct4/Sox2:UTF1 structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3') | polymer | 22 | 6757.4 | 1 | Mus musculus | ||
| 2 | B (B) | DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3') | polymer | 21 | 6455.2 | 1 | Mus musculus | ||
| 3 | C (D) | Transcription factor SOX-2 | polymer | 83 | 10092.9 | 1 | UniProt (P48432) Pfam (PF00505) | Mus musculus (Mouse) | |
| 4 | D (E) | POU domain, class 5, transcription factor 1 | polymer | 154 | 17831.7 | 1 | UniProt (P20263) Pfam (PF00157) Pfam (PF00046) | Mus musculus (Mouse) | NF-A3,Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3 |
Sequence modifications
D: 44 - 123 (UniProt: P48432)
E: 133 - 284 (UniProt: P20263)
| PDB | External Database | Details |
|---|---|---|
| Gly 41 | - | expression tag |
| Ala 42 | - | expression tag |
| Met 43 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 131 | - | expression tag |
| Ala 132 | - | expression tag |
| Ser 180 | Cys 178 | engineered mutation |
| Ser 193 | Cys 191 | engineered mutation |
| Ser 216 | Cys 214 | engineered mutation |
| Ser 247 | Cys 245 | engineered mutation |
| Ser 274 | Cys 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 41137.1 | |
| All* | Total formula weight | 41137.1 |
