6HT5

Oct4/Sox2:UTF1 structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3')	polymer	22	6757.4	1		Mus musculus
2	B (B)	DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3')	polymer	21	6455.2	1		Mus musculus
3	C (D)	Transcription factor SOX-2	polymer	83	10092.9	1	UniProt (P48432) Pfam (PF00505)	Mus musculus (Mouse)
4	D (E)	POU domain, class 5, transcription factor 1	polymer	154	17831.7	1	UniProt (P20263) Pfam (PF00157) Pfam (PF00046)	Mus musculus (Mouse)	NF-A3,Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3

Sequence modifications

D: 44 - 123 (UniProt: P48432)

PDB	External Database	Details
Gly 41	-	expression tag
Ala 42	-	expression tag
Met 43	-	expression tag

E: 133 - 284 (UniProt: P20263)

PDB	External Database	Details
Gly 131	-	expression tag
Ala 132	-	expression tag
Ser 180	Cys 178	engineered mutation
Ser 193	Cys 191	engineered mutation
Ser 216	Cys 214	engineered mutation
Ser 247	Cys 245	engineered mutation
Ser 274	Cys 272	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	41137.1
All*	Total formula weight	41137.1

*Water molecules are not included.