6HRH
Structure of human erythroid-specific 5'-aminolevulinate synthase, ALAS2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A | 5-aminolevulinate synthase, erythroid-specific, mitochondrial | polymer | 469 | 52250.6 | 2 | UniProt (P22557) Pfam (PF00155) In PDB | Homo sapiens (Human) | ALAS-E,5-aminolevulinic acid synthase 2,Delta-ALA synthase 2,Delta-aminolevulinate synthase 2 |
2 | B, A | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
3 | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
B, A: 143 - 587 (UniProt: P22557)
PDB | External Database | Details |
---|---|---|
Met 119 | - | initiating methionine |
Gly 120 | - | expression tag |
His 121 | - | expression tag |
His 122 | - | expression tag |
His 123 | - | expression tag |
His 124 | - | expression tag |
His 125 | - | expression tag |
His 126 | - | expression tag |
Ser 127 | - | expression tag |
Ser 128 | - | expression tag |
Gly 129 | - | expression tag |
Val 130 | - | expression tag |
Asp 131 | - | expression tag |
Leu 132 | - | expression tag |
Gly 133 | - | expression tag |
Thr 134 | - | expression tag |
Glu 135 | - | expression tag |
Asn 136 | - | expression tag |
Leu 137 | - | expression tag |
Tyr 138 | - | expression tag |
Phe 139 | - | expression tag |
Gln 140 | - | expression tag |
Ser 141 | - | expression tag |
Met 142 | - | expression tag |
Val 221 | Ala 221 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 104501.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 494.3 | |
All* | Total formula weight | 104995.4 |