6HP0

Complex of Neuraminidase from H1N1 Influenza Virus in Complex with Oseltamivir Triazol Derivative

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Neuraminidase	polymer	388	42727.6	4	UniProt (C6KP13) Pfam (PF00064)	Influenza A virus (A/Texas/17/2009(H1N1))
2	E, G, H (E, G, H)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	3	In PDB GlyTouCan (G21290RB)
3	F, J (F, J)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	2	In PDB GlyTouCan (G86851RC)
4	I (I)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1057.0	1	In PDB GlyTouCan (G82348BZ)
5	CA, DA, K, L, NA... (B, A, C, D)	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)
6	EA, M, PA, WA (B, A, C, D)	(3~{R},4~{R},5~{S})-4-acetamido-5-[4-(hydroxymethyl)-1,2,3-triazol-1-yl]-3-pentan-3-yloxy-cyclohexene-1-carboxylic acid	non-polymer		366.4	4	Chemie (GJT)
7	FA, GA, N, QA, XA... (B, A, C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
8	AA, AB, BA, BB, CB... (A, D, B, C)	1,2-ETHANEDIOL	non-polymer		62.1	29	Chemie (EDO)
9	FB (D)	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
10	GB, HB, IB, JB (A, B, C, D)	water	water		18.0	1399	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	170910.5
Branched	Number of molecules	6
	Total formula weight	3503.3
Non-Polymers*	Number of molecules	48
	Total formula weight	5063.7
All*	Total formula weight	179477.5

*Water molecules are not included.