6HN8
Structure of BM3 heme domain in complex with troglitazone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bifunctional cytochrome P450/NADPH--P450 reductase | polymer | 457 | 52410.8 | 2 | UniProt (A0A1Q8UP87) UniProt (by SIFTS) (P14779) | Bacillus megaterium | |
| 2 | C, E (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | D, F (A, B) | (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE | non-polymer | 441.5 | 2 | Chemie (TDZ) PubChem (5591) PubChem (29010888) PubChem (60092044) PubChem (87873950) PubChem (90291732) PubChem (88924867) PubChem (6518172) PubChem (9803337) PubChem (9824580) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 805 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 455 (UniProt: A0A1Q8UP87)
| PDB | External Database | Details |
|---|---|---|
| Asx -1 | - | expression tag |
| Phe 82 | Ala 83 | engineered mutation |
| Val 87 | Phe 88 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104821.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2116.1 | |
| All* | Total formula weight | 106937.6 |
