6HN6

A revisited version of the apo structure of the ligand-binding domain of the human nuclear receptor RXR-ALPHA

Replaces:  1LBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Retinoic acid receptor RXR-alpha	polymer	282	31702.2	1	UniProt (P19793) Pfam (PF00104)	Homo sapiens (Human)	Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha
2	B, C, D, E (A)	3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE	non-polymer		614.9	4	Chemie (CPS) PubChem (16396400) PubChem (18397788) PubChem (50987450) PubChem (51028881) PubChem (51028882) PubChem (177530666) PubChem (24883538) PubChem (44120060) PubChem (44450441) PubChem (53393728) PubChem (53229977) PubChem (107670) PubChem (71774074) PubChem (58528211) PubChem (90488808) PubChem (91746229) PubChem (91809267) PubChem (457060) PubChem (102565428) PubChem (122361936) PubChem (122362044) PubChem (3659871) PubChem (131632459) PubChem (133645855) PubChem (9895216) PubChem (10371606) PubChem (137704711) PubChem (146159681)
3	F (A)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

A: 201 - 462 (UniProt: P19793)

PDB	External Database	Details
Met 181	-	initiating methionine
Gly 182	-	expression tag
Ser 183	-	expression tag
Ser 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
Ser 191	-	expression tag
Ser 192	-	expression tag
Gly 193	-	expression tag
Leu 194	-	expression tag
Val 195	-	expression tag
Pro 196	-	expression tag
Arg 197	-	expression tag
Gly 198	-	expression tag
Ser 199	-	expression tag
His 200	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	31702.2
Non-Polymers*	Number of molecules	4
	Total formula weight	2459.5
All*	Total formula weight	34161.7

*Water molecules are not included.