6HMV

Crystal structure of human ACBD3 GOLD domain in complex with 3A protein of enterovirus-D68 (fusion protein, LVVY mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Golgi resident protein GCP60	polymer	168	19389.3	1	UniProt (Q9H3P7) Pfam (PF13897)	Homo sapiens (Human)	Acyl-CoA-binding domain-containing protein 3,Golgi complex-associated protein 1,GOCAP1,Golgi phosphoprotein 1,GOLPH1,PBR- and PKA-associated protein 7,Peripheral benzodiazepine receptor-associated protein PAP7
2	B (B)	Genome polyprotein	polymer	50	5320.9	1	UniProt (A0A2K9Y515) Pfam (PF08727) UniProt (by SIFTS) (Q68T42)	Enterovirus D68

Sequence modifications

A: 364 - 528 (UniProt: Q9H3P7)

PDB	External Database	Details
Gly 361	-	expression tag
Ala 362	-	expression tag
Met 363	-	expression tag

B: 16 - 60 (UniProt: A0A2K9Y515)

PDB	External Database	Details
Gly 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Ser 14	-	expression tag
Gly 15	-	expression tag
Ala 25	Leu 1463	engineered mutation
Ala 29	Val 1467	engineered mutation
Ala 34	Val 1472	engineered mutation
Ala 37	Tyr 1475	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24710.2
All*	Total formula weight	24710.2

*Water molecules are not included.