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6HKY

Eg5-inhibitor complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CKinesin-like protein KIF11polymer36841055.63UniProt (P52732)
Pfam (PF00225)
In PDB
Homo sapiens (Human)Kinesin-like protein 1,Kinesin-like spindle protein HKSP,Kinesin-related motor protein Eg5,Thyroid receptor-interacting protein 5,TRIP-5
2A, B, CADENOSINE-5'-DIPHOSPHATEnon-polymer427.23Chemie (ADP)
3A, B, CMAGNESIUM IONnon-polymer24.33Chemie (MG)
4A, B, C(2~{S})-2-(3-azanylpropyl)-5-[2,5-bis(fluoranyl)phenyl]-~{N}-methoxy-~{N}-methyl-2-phenyl-1,3,4-thiadiazole-3-carboxamidenon-polymer420.53Chemie (GCE)
5waterwater18.0255Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight123166.7
Non-Polymers*Number of molecules9
Total formula weight2615.9
All*Total formula weight125782.7
*Water molecules are not included.

223166

PDB entries from 2024-07-31

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