6HKS
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Tyrosine-protein phosphatase non-receptor type 3 | polymer | 114 | 12709.2 | 6 | UniProt (P26045) Pfam (PF00595) | Homo sapiens (Human) | Protein-tyrosine phosphatase H1,PTP-H1 |
| 2 | G, H, I, J, K... (G, H, I, J, K...) | Protein E6 | polymer | 11 | 1393.6 | 6 | UniProt (P03126) | Human papillomavirus type 16 | |
| 3 | M, N, O, P, Q... (A, B, C, E, F) | IODIDE ION | non-polymer | 126.9 | 6 | Chemie (IOD) | |||
| 4 | AA, BA, CA, DA, S... (I, J, K, L, A...) | water | water | 18.0 | 233 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 489 - 597 (UniProt: P26045)
| PDB | External Database | Details |
|---|---|---|
| Gly 484 | - | expression tag |
| Ala 485 | - | expression tag |
| Met 486 | - | expression tag |
| Gly 487 | - | expression tag |
| Ser 488 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 84616.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 761.4 | |
| All* | Total formula weight | 85378.2 |
