6HKS

Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Tyrosine-protein phosphatase non-receptor type 3	polymer	114	12709.2	6	UniProt (P26045) Pfam (PF00595) In PDB	Homo sapiens (Human)	Protein-tyrosine phosphatase H1,PTP-H1
2	G, H, I, J, K...	Protein E6	polymer	11	1393.6	6	UniProt (P03126) In PDB	Human papillomavirus type 16
3	A, B, C, E, F	IODIDE ION	non-polymer		126.9	6	Chemie (IOD)
4		water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 489 - 597 (UniProt: P26045)

PDB	External Database	Details
Gly 484	-	expression tag
Ala 485	-	expression tag
Met 486	-	expression tag
Gly 487	-	expression tag
Ser 488	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	84616.8
Non-Polymers*	Number of molecules	6
	Total formula weight	761.4
All*	Total formula weight	85378.2

*Water molecules are not included.