6HK6
Human RIOK2 bound to inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Serine/threonine-protein kinase RIO2 | polymer | 330 | 38264.8 | 10 | UniProt (Q9BVS4) Pfam (PF09202) Pfam (PF01163) In PDB | Homo sapiens (Human) | RIO kinase 2 |
2 | F, G, H, I, J... | 2-naphthalen-2-yl-~{N}-pyridin-2-yl-ethanamide | non-polymer | 262.3 | 10 | Chemie (G8H) | |||
3 | H, A, C | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
4 | F, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
5 | E, H, B, D | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
6 | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 329 (UniProt: Q9BVS4)
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Tyr 144 | His 144 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 382647.9 | |
Non-Polymers* | Number of molecules | 25 |
Total formula weight | 4152.6 | |
All* | Total formula weight | 386800.4 |