6HK6
Human RIOK2 bound to inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Serine/threonine-protein kinase RIO2 | polymer | 330 | 38264.8 | 10 | UniProt (Q9BVS4) Pfam (PF09202) Pfam (PF01163) | Homo sapiens (Human) | RIO kinase 2 |
| 2 | BA, DA, EA, HA, IA... (F, G, H, I, J...) | 2-naphthalen-2-yl-~{N}-pyridin-2-yl-ethanamide | non-polymer | 262.3 | 10 | Chemie (G8H) | |||
| 3 | GA, L, M, W (H, A, C) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | CA, N, O, P, S... (F, A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 5 | AA, FA, R, Y (E, H, B, D) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 6 | JA, KA, LA, MA, NA... (A, B, C, D, E...) | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 1 - 329 (UniProt: Q9BVS4)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Tyr 144 | His 144 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 382647.9 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 4152.6 | |
| All* | Total formula weight | 386800.4 |
