Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6HIX

Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A0	bl27m	polymer	185	21793.1	1	UniProt (A0A1G4I8T3) In PDB	Trypanosoma brucei brucei
2	A1	bl28m	polymer	241	28051.4	1	UniProt (Q586A2) In PDB	Trypanosoma brucei brucei
3	A2	ul29m	polymer	471	54045.4	1	UniProt (Q38EM7) Pfam (PF06984) In PDB	Trypanosoma brucei brucei
4	A3	ul30m	polymer	218	25204.3	1	UniProt (C9ZY77) In PDB	Trypanosoma brucei brucei
5	A4	bl31m	polymer	183	21083.2	1	UniProt (Q38AB0) In PDB	Trypanosoma brucei brucei
6	A5	bl32m	polymer	80	9745.7	1	UniProt (Q584F4) In PDB	Trypanosoma brucei brucei
7	A6	bl33m	polymer	114	13042.7	1	UniProt (Q581Q0) In PDB	Trypanosoma brucei brucei
8	A8	bl35m	polymer	181	21661.5	1	UniProt (D0A1K1) In PDB	Trypanosoma brucei brucei
9	A9	bl36m	polymer	184	21795.2	1	UniProt (C9ZMA9) In PDB	Trypanosoma brucei brucei
10	AE	Ribosomal protein L3 mitochondrial, putative	polymer	473	55073.7	1	UniProt (Q580R4) Pfam (PF00297) In PDB	Trypanosoma brucei brucei
11	AF	Ribosomal protein L4/L1 family, putative	polymer	459	53156.7	1	UniProt (A0A1G4HYD1) Pfam (PF00573) In PDB	Trypanosoma brucei brucei
12	AI	bl9m	polymer	263	31032.7	1	UniProt (Q57UC5) Pfam (PF01281) In PDB	Trypanosoma brucei brucei
13	AJ	ul10m	polymer	177	20283.6	1	UniProt (C9ZPD1) In PDB	Trypanosoma brucei brucei
14	AK	Ribosomal protein L11, putative	polymer	342	40252.8	1	UniProt (Q586R9) Pfam (PF03946) Pfam (PF00298) In PDB	Trypanosoma brucei brucei
15	AN	50S ribosomal protein L13, putative	polymer	202	24341.3	1	UniProt (Q580D5) Pfam (PF00572) In PDB	Trypanosoma brucei brucei
16	AP	ul15m	polymer	374	43780.0	1	UniProt (Q57U68) Pfam (PF00828) In PDB	Trypanosoma brucei brucei
17	AQ	50S ribosomal protein L16, putative	polymer	167	19158.1	1	UniProt (Q57UM6) Pfam (PF00252) In PDB	Trypanosoma brucei brucei
18	AR	50S ribosomal protein L17, putative	polymer	301	35117.8	1	UniProt (Q57YI7) Pfam (PF01196) In PDB	Trypanosoma brucei brucei
19	AT	bl19m	polymer	144	16931.5	1	UniProt (Q4GZ98) In PDB	Trypanosoma brucei brucei
20	AU	bl20m	polymer	213	24393.9	1	UniProt (Q383R2) In PDB	Trypanosoma brucei brucei
21	AV	bl21m	polymer	188	20895.3	1	UniProt (C9ZT11) Pfam (PF00829) In PDB	Trypanosoma brucei brucei
22	AW	ul22m	polymer	278	32083.3	1	UniProt (C9ZSI8) Pfam (PF00237) In PDB	Trypanosoma brucei brucei
23	AX	ul23m	polymer	246	28822.9	1	UniProt (Q387G3) In PDB	Trypanosoma brucei brucei
24	AY	ul24m	polymer	378	43999.0	1	UniProt (C9ZK52) In PDB	Trypanosoma brucei brucei
25	Ab	ml38	polymer	507	58437.9	1	UniProt (Q381T7) In PDB	Trypanosoma brucei brucei
26	Ad	ml40	polymer	289	33646.1	1	UniProt (D0A511) In PDB	Trypanosoma brucei brucei
27	Ae	ml41	polymer	197	22556.9	1	UniProt (D0A8I6) In PDB	Trypanosoma brucei brucei
28	Af	ml42	polymer	189	21602.6	1	UniProt (Q383S1) In PDB	Trypanosoma brucei brucei
29	Ag	ml43	polymer	260	31300.4	1	UniProt (Q583E5) Pfam (PF05047) In PDB	Trypanosoma brucei brucei
30	Aj	ml46	polymer	296	33984.2	1	UniProt (C9ZT91) Pfam (PF11788) In PDB	Trypanosoma brucei brucei
31	Al	ml49	polymer	218	24501.5	1	UniProt (Q57Z82) In PDB	Trypanosoma brucei brucei
32	Ao	ml52	polymer	259	29176.0	1	UniProt (Q385V2) In PDB	Trypanosoma brucei brucei
33	Ap	ml53	polymer	309	35656.4	1	UniProt (Q57YA9) In PDB	Trypanosoma brucei brucei
34	At	ml63	polymer	154	18213.9	1	UniProt (C9ZU82) In PDB	Trypanosoma brucei brucei
35	Av	ml64	polymer	242	28546.0	1	UniProt (Q383B7) In PDB	Trypanosoma brucei brucei
36	AB	bL12m	polymer	56	3998.4	1		Trypanosoma brucei brucei
37	AC, AD	bL12m	polymer	28	2008.2	2		Trypanosoma brucei brucei
38	AG	bL12m	polymer	27	1937.1	1		Trypanosoma brucei brucei
39	AA	12S rRNA	polymer	1178	376748.5	1	GenBank (343546)	Trypanosoma brucei brucei
40	BA	ml67	polymer	831	93569.3	1	UniProt (D0A5V6) In PDB	Trypanosoma brucei brucei
41	BB	ml68	polymer	541	62806.3	1	UniProt (D0A135) In PDB	Trypanosoma brucei brucei
42	BC	ml69	polymer	523	59010.9	1	UniProt (Q584V5) Pfam (PF00501) In PDB	Trypanosoma brucei brucei
43	BD	mL70	polymer	547	62442.4	1		Trypanosoma brucei brucei
44	BE	ml71	polymer	449	50313.8	1	UniProt (Q57WG1) In PDB	Trypanosoma brucei brucei
45	BF	ml72	polymer	426	49407.0	1	UniProt (C9ZR63) In PDB	Trypanosoma brucei brucei
46	BG	ml73	polymer	378	41857.9	1	UniProt (Q57Y49) In PDB	Trypanosoma brucei brucei
47	BH	ml74	polymer	349	39765.2	1	UniProt (Q38AM5) In PDB	Trypanosoma brucei brucei
48	BI	ml75	polymer	343	39841.6	1	UniProt (Q38CK0) In PDB	Trypanosoma brucei brucei
49	BJ	ml76	polymer	333	39638.9	1	UniProt (Q383M2) In PDB	Trypanosoma brucei brucei
50	BK	Chaperone protein DNAj, putative	polymer	386	43819.7	1	UniProt (C9ZQR6) Pfam (PF00226) In PDB	Trypanosoma brucei brucei
51	BL	ml78	polymer	312	35104.5	1	UniProt (D0A4P5) In PDB	Trypanosoma brucei brucei
52	BM	ml79	polymer	283	33079.6	1	UniProt (Q381N5) In PDB	Trypanosoma brucei brucei
53	BN	ml80	polymer	302	34883.3	1	UniProt (Q585A3) In PDB	Trypanosoma brucei brucei
54	BO	ml81	polymer	262	29284.5	1	UniProt (D0A755) In PDB	Trypanosoma brucei brucei
55	BP	ml82	polymer	266	29283.7	1	UniProt (D0A0S6) In PDB	Trypanosoma brucei brucei
56	BQ	Peptidyl-prolyl cis-trans isomerase	polymer	231	25579.0	1	UniProt (Q57WF8) Pfam (PF00160) In PDB	Trypanosoma brucei brucei	PPIase
57	BR	ml84	polymer	205	24773.6	1	UniProt (Q586A6) In PDB	Trypanosoma brucei brucei
58	BS	ml85	polymer	198	22658.0	1	UniProt (Q38FG8) In PDB	Trypanosoma brucei brucei
59	BT	ml86	polymer	191	22376.2	1	UniProt (C9ZPU8) In PDB	Trypanosoma brucei brucei
60	BU	ml87	polymer	185	22337.5	1	UniProt (D0A7Z9) In PDB	Trypanosoma brucei brucei
61	BV	ml88	polymer	190	22255.6	1	UniProt (C9ZUW3) In PDB	Trypanosoma brucei brucei
62	BW	ml89	polymer	188	22213.4	1	UniProt (Q57WW5) In PDB	Trypanosoma brucei brucei
63	BX	ml90	polymer	190	22123.4	1	UniProt (Q585P1) Pfam (PF00412) In PDB	Trypanosoma brucei brucei
64	BY	ml91	polymer	172	20618.5	1	UniProt (Q580U5) In PDB	Trypanosoma brucei brucei
65	BZ	Peptidyl-prolyl cis-trans isomerase	polymer	190	20542.3	1	UniProt (Q383Y4) Pfam (PF00160) In PDB	Trypanosoma brucei brucei	PPIase
66	Ba	ml93	polymer	153	18929.7	1	UniProt (D0A4T0) In PDB	Trypanosoma brucei brucei
67	Bb	ml94	polymer	162	17831.0	1	UniProt (Q38EP7) In PDB	Trypanosoma brucei brucei
68	Bc	ml95	polymer	146	17803.4	1	UniProt (Q389K3) In PDB	Trypanosoma brucei brucei
69	Bd	ml96	polymer	144	16387.7	1	UniProt (Q381W9) In PDB	Trypanosoma brucei brucei
70	Be	ml97	polymer	113	12974.8	1	UniProt (Q388L8) In PDB	Trypanosoma brucei brucei
71	Bf	ml98	polymer	113	12968.6	1	UniProt (Q388M2) In PDB	Trypanosoma brucei brucei
72	Bg	ml99	polymer	105	12335.0	1	UniProt (Q587H8) In PDB	Trypanosoma brucei brucei
73	Bh	ml100	polymer	92	10600.4	1	UniProt (A0A1G4HYZ0) In PDB	Trypanosoma brucei brucei
74	UA	UNK	polymer	46	3932.8	1		Trypanosoma brucei brucei
75	UB	UNK	polymer	40	3422.2	1		Trypanosoma brucei brucei
76	UC, UH	UNK	polymer	12	1039.3	2		Trypanosoma brucei brucei
77	UD	UNK	polymer	177	15081.6	1		Trypanosoma brucei brucei
78	UE	UNK	polymer	22	1890.3	1		Trypanosoma brucei brucei
79	UF, UG, UN	UNK	polymer	24	2060.5	3		Trypanosoma brucei brucei
80	UI	UNK	polymer	17	1464.8	1		Trypanosoma brucei brucei
81	UK	UNK	polymer	10	869.1	1		Trypanosoma brucei brucei
82	UL	UNK	polymer	15	1294.6	1		Trypanosoma brucei brucei
83	UM	UNK	polymer	6	528.6	1		Trypanosoma brucei brucei
84	UU	UNK	polymer	11	954.2	1		Trypanosoma brucei brucei
85	UV, UX	UNK	polymer	8	698.9	2		Trypanosoma brucei brucei
86	UW	UNK	polymer	7	613.7	1		Trypanosoma brucei brucei
87	Bh, A5, A9, BX, Be	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
88	Av	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
89	AA	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)

Sequence modifications

A2: 1 - 471 (UniProt: Q38EM7)

PDB	External Database	Details
Gly 238	Ala 238	conflict

AY: 1 - 378 (UniProt: C9ZK52)

PDB	External Database	Details
Glu 345	Val 345	conflict

Ab: 1 - 507 (UniProt: Q381T7)

PDB	External Database	Details
Ser 290	Phe 290	conflict
Glu 299	Lys 299	conflict
Asn 471	Ile 471	conflict

Ap: 1 - 309 (UniProt: Q57YA9)

PDB	External Database	Details
Leu 2	Ser 2	conflict

Av: 1 - 242 (UniProt: Q383B7)

PDB	External Database	Details
Arg 164	Gln 164	conflict

AA: 1 - 1178 (GenBank: 343546)

PDB	External Database	Details
A 448	U 1811	conflict
A 622	U 1985	conflict
A 636	G 1999	conflict
G 702	A 2065	conflict
C 706	U 2069	conflict
C 743	G 2106	conflict
G 752	A 2115	conflict
U 757	A 2120	conflict
U 760	G 2123	conflict
U 762	G 2125	conflict
G 789	C 2152	conflict
G 793	U 2156	conflict
A 875	G 2238	conflict
G 876	A 2239	conflict
A 877	G 2240	conflict

BC: 1 - 523 (UniProt: Q584V5)

PDB	External Database	Details
Pro 29	Ser 29	conflict
Gly 42	Ser 42	conflict

BF: 1 - 426 (UniProt: C9ZR63)

PDB	External Database	Details
Ile 296	Thr 296	conflict

BG: 1 - 378 (UniProt: Q57Y49)

PDB	External Database	Details
Phe 185	Leu 185	conflict

BI: 1 - 342 (UniProt: Q38CK0)

PDB	External Database	Details
Asn 227	Asp 227	conflict
Arg 319	Gln 319	conflict
Ala 343	-	expression tag

BJ: 1 - 333 (UniProt: Q383M2)

PDB	External Database	Details
Glu 329	Ala 329	conflict

BK: 1 - 386 (UniProt: C9ZQR6)

PDB	External Database	Details
Val 348	Leu 348	conflict

BN: -43 - 258 (UniProt: Q585A3)

PDB	External Database	Details
Thr 145	Ala 189	conflict

BS: 1 - 198 (UniProt: Q38FG8)

PDB	External Database	Details
Ile 45	Val 45	conflict
Unk 173	Leu 173	conflict

BT: 1 - 191 (UniProt: C9ZPU8)

PDB	External Database	Details
Arg 70	Gln 70	conflict

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	91
Polymers	Total formula weight	2559193.6
Non-Polymers*	Number of molecules	14
Non-Polymers*	Total formula weight	1226.0
All*	Total formula weight	2560419.6

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)