Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6HIX

Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A0)	bl27m	polymer	185	21793.1	1	UniProt (A0A1G4I8T3)	Trypanosoma brucei brucei
2	B (A1)	bl28m	polymer	241	28051.4	1	UniProt (Q586A2)	Trypanosoma brucei brucei
3	C (A2)	ul29m	polymer	471	54045.4	1	UniProt (Q38EM7) Pfam (PF06984)	Trypanosoma brucei brucei
4	D (A3)	ul30m	polymer	218	25204.3	1	UniProt (C9ZY77)	Trypanosoma brucei brucei
5	E (A4)	bl31m	polymer	183	21083.2	1	UniProt (Q38AB0)	Trypanosoma brucei brucei
6	F (A5)	bl32m	polymer	80	9745.7	1	UniProt (Q584F4)	Trypanosoma brucei brucei
7	G (A6)	bl33m	polymer	114	13042.7	1	UniProt (Q581Q0)	Trypanosoma brucei brucei
8	H (A8)	bl35m	polymer	181	21661.5	1	UniProt (D0A1K1)	Trypanosoma brucei brucei
9	I (A9)	bl36m	polymer	184	21795.2	1	UniProt (C9ZMA9)	Trypanosoma brucei brucei
10	J (AE)	Ribosomal protein L3 mitochondrial, putative	polymer	473	55073.7	1	UniProt (Q580R4) Pfam (PF00297)	Trypanosoma brucei brucei
11	K (AF)	Ribosomal protein L4/L1 family, putative	polymer	459	53156.7	1	UniProt (A0A1G4HYD1) Pfam (PF00573)	Trypanosoma brucei brucei
12	L (AI)	bl9m	polymer	263	31032.7	1	UniProt (Q57UC5) Pfam (PF01281)	Trypanosoma brucei brucei
13	M (AJ)	ul10m	polymer	177	20283.6	1	UniProt (C9ZPD1)	Trypanosoma brucei brucei
14	N (AK)	Ribosomal protein L11, putative	polymer	342	40252.8	1	UniProt (Q586R9) Pfam (PF03946) Pfam (PF00298)	Trypanosoma brucei brucei
15	O (AN)	50S ribosomal protein L13, putative	polymer	202	24341.3	1	UniProt (Q580D5) Pfam (PF00572)	Trypanosoma brucei brucei
16	P (AP)	ul15m	polymer	374	43780.0	1	UniProt (Q57U68) Pfam (PF00828)	Trypanosoma brucei brucei
17	Q (AQ)	50S ribosomal protein L16, putative	polymer	167	19158.1	1	UniProt (Q57UM6) Pfam (PF00252)	Trypanosoma brucei brucei
18	R (AR)	50S ribosomal protein L17, putative	polymer	301	35117.8	1	UniProt (Q57YI7) Pfam (PF01196)	Trypanosoma brucei brucei
19	S (AT)	bl19m	polymer	144	16931.5	1	UniProt (Q4GZ98)	Trypanosoma brucei brucei
20	T (AU)	bl20m	polymer	213	24393.9	1	UniProt (Q383R2)	Trypanosoma brucei brucei
21	U (AV)	bl21m	polymer	188	20895.3	1	UniProt (C9ZT11) Pfam (PF00829)	Trypanosoma brucei brucei
22	V (AW)	ul22m	polymer	278	32083.3	1	UniProt (C9ZSI8) Pfam (PF00237)	Trypanosoma brucei brucei
23	W (AX)	ul23m	polymer	246	28822.9	1	UniProt (Q387G3)	Trypanosoma brucei brucei
24	X (AY)	ul24m	polymer	378	43999.0	1	UniProt (C9ZK52)	Trypanosoma brucei brucei
25	Y (Ab)	ml38	polymer	507	58437.9	1	UniProt (Q381T7)	Trypanosoma brucei brucei
26	Z (Ad)	ml40	polymer	289	33646.1	1	UniProt (D0A511)	Trypanosoma brucei brucei
27	AA (Ae)	ml41	polymer	197	22556.9	1	UniProt (D0A8I6)	Trypanosoma brucei brucei
28	BA (Af)	ml42	polymer	189	21602.6	1	UniProt (Q383S1)	Trypanosoma brucei brucei
29	CA (Ag)	ml43	polymer	260	31300.4	1	UniProt (Q583E5) Pfam (PF05047)	Trypanosoma brucei brucei
30	DA (Aj)	ml46	polymer	296	33984.2	1	UniProt (C9ZT91) Pfam (PF11788)	Trypanosoma brucei brucei
31	EA (Al)	ml49	polymer	218	24501.5	1	UniProt (Q57Z82)	Trypanosoma brucei brucei
32	FA (Ao)	ml52	polymer	259	29176.0	1	UniProt (Q385V2)	Trypanosoma brucei brucei
33	GA (Ap)	ml53	polymer	309	35656.4	1	UniProt (Q57YA9)	Trypanosoma brucei brucei
34	HA (At)	ml63	polymer	154	18213.9	1	UniProt (C9ZU82)	Trypanosoma brucei brucei
35	IA (Av)	ml64	polymer	242	28546.0	1	UniProt (Q383B7)	Trypanosoma brucei brucei
36	JA (AB)	bL12m	polymer	56	3998.4	1		Trypanosoma brucei brucei
37	KA, LA (AC, AD)	bL12m	polymer	28	2008.2	2		Trypanosoma brucei brucei
38	MA (AG)	bL12m	polymer	27	1937.1	1		Trypanosoma brucei brucei
39	NA (AA)	12S rRNA	polymer	1178	376748.5	1	GenBank (343546)	Trypanosoma brucei brucei
40	OA (BA)	ml67	polymer	831	93569.3	1	UniProt (D0A5V6)	Trypanosoma brucei brucei
41	PA (BB)	ml68	polymer	541	62806.3	1	UniProt (D0A135)	Trypanosoma brucei brucei
42	QA (BC)	ml69	polymer	523	59010.9	1	UniProt (Q584V5) Pfam (PF00501)	Trypanosoma brucei brucei
43	RA (BD)	mL70	polymer	547	62442.4	1		Trypanosoma brucei brucei
44	SA (BE)	ml71	polymer	449	50313.8	1	UniProt (Q57WG1)	Trypanosoma brucei brucei
45	TA (BF)	ml72	polymer	426	49407.0	1	UniProt (C9ZR63)	Trypanosoma brucei brucei
46	UA (BG)	ml73	polymer	378	41857.9	1	UniProt (Q57Y49)	Trypanosoma brucei brucei
47	VA (BH)	ml74	polymer	349	39765.2	1	UniProt (Q38AM5)	Trypanosoma brucei brucei
48	WA (BI)	ml75	polymer	343	39841.6	1	UniProt (Q38CK0)	Trypanosoma brucei brucei
49	XA (BJ)	ml76	polymer	333	39638.9	1	UniProt (Q383M2)	Trypanosoma brucei brucei
50	YA (BK)	Chaperone protein DNAj, putative	polymer	386	43819.7	1	UniProt (C9ZQR6) Pfam (PF00226)	Trypanosoma brucei brucei
51	ZA (BL)	ml78	polymer	312	35104.5	1	UniProt (D0A4P5)	Trypanosoma brucei brucei
52	AB (BM)	ml79	polymer	283	33079.6	1	UniProt (Q381N5)	Trypanosoma brucei brucei
53	BB (BN)	ml80	polymer	302	34883.3	1	UniProt (Q585A3)	Trypanosoma brucei brucei
54	CB (BO)	ml81	polymer	262	29284.5	1	UniProt (D0A755)	Trypanosoma brucei brucei
55	DB (BP)	ml82	polymer	266	29283.7	1	UniProt (D0A0S6)	Trypanosoma brucei brucei
56	EB (BQ)	Peptidyl-prolyl cis-trans isomerase	polymer	231	25579.0	1	UniProt (Q57WF8) Pfam (PF00160)	Trypanosoma brucei brucei	PPIase
57	FB (BR)	ml84	polymer	205	24773.6	1	UniProt (Q586A6)	Trypanosoma brucei brucei
58	GB (BS)	ml85	polymer	198	22658.0	1	UniProt (Q38FG8)	Trypanosoma brucei brucei
59	HB (BT)	ml86	polymer	191	22376.2	1	UniProt (C9ZPU8)	Trypanosoma brucei brucei
60	IB (BU)	ml87	polymer	185	22337.5	1	UniProt (D0A7Z9)	Trypanosoma brucei brucei
61	JB (BV)	ml88	polymer	190	22255.6	1	UniProt (C9ZUW3)	Trypanosoma brucei brucei
62	KB (BW)	ml89	polymer	188	22213.4	1	UniProt (Q57WW5)	Trypanosoma brucei brucei
63	LB (BX)	ml90	polymer	190	22123.4	1	UniProt (Q585P1) Pfam (PF00412)	Trypanosoma brucei brucei
64	MB (BY)	ml91	polymer	172	20618.5	1	UniProt (Q580U5)	Trypanosoma brucei brucei
65	NB (BZ)	Peptidyl-prolyl cis-trans isomerase	polymer	190	20542.3	1	UniProt (Q383Y4) Pfam (PF00160)	Trypanosoma brucei brucei	PPIase
66	OB (Ba)	ml93	polymer	153	18929.7	1	UniProt (D0A4T0)	Trypanosoma brucei brucei
67	PB (Bb)	ml94	polymer	162	17831.0	1	UniProt (Q38EP7)	Trypanosoma brucei brucei
68	QB (Bc)	ml95	polymer	146	17803.4	1	UniProt (Q389K3)	Trypanosoma brucei brucei
69	RB (Bd)	ml96	polymer	144	16387.7	1	UniProt (Q381W9)	Trypanosoma brucei brucei
70	SB (Be)	ml97	polymer	113	12974.8	1	UniProt (Q388L8)	Trypanosoma brucei brucei
71	TB (Bf)	ml98	polymer	113	12968.6	1	UniProt (Q388M2)	Trypanosoma brucei brucei
72	UB (Bg)	ml99	polymer	105	12335.0	1	UniProt (Q587H8)	Trypanosoma brucei brucei
73	VB (Bh)	ml100	polymer	92	10600.4	1	UniProt (A0A1G4HYZ0)	Trypanosoma brucei brucei
74	WB (UA)	UNK	polymer	46	3932.8	1		Trypanosoma brucei brucei
75	XB (UB)	UNK	polymer	40	3422.2	1		Trypanosoma brucei brucei
76	DC, YB (UC, UH)	UNK	polymer	12	1039.3	2		Trypanosoma brucei brucei
77	ZB (UD)	UNK	polymer	177	15081.6	1		Trypanosoma brucei brucei
78	AC (UE)	UNK	polymer	22	1890.3	1		Trypanosoma brucei brucei
79	BC, CC, IC (UF, UG, UN)	UNK	polymer	24	2060.5	3		Trypanosoma brucei brucei
80	EC (UI)	UNK	polymer	17	1464.8	1		Trypanosoma brucei brucei
81	FC (UK)	UNK	polymer	10	869.1	1		Trypanosoma brucei brucei
82	GC (UL)	UNK	polymer	15	1294.6	1		Trypanosoma brucei brucei
83	HC (UM)	UNK	polymer	6	528.6	1		Trypanosoma brucei brucei
84	JC (UU)	UNK	polymer	11	954.2	1		Trypanosoma brucei brucei
85	KC, MC (UV, UX)	UNK	polymer	8	698.9	2		Trypanosoma brucei brucei
86	LC (UW)	UNK	polymer	7	613.7	1		Trypanosoma brucei brucei
87	AD, NC, OC, XC, YC... (Bh, A5, A9, BX, Be)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
88	PC (Av)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	1	Chemie (NAD)
89	QC, RC, SC, TC, UC... (AA)	MAGNESIUM ION	non-polymer		24.3	7	Chemie (MG)

Sequence modifications

A2: 1 - 471 (UniProt: Q38EM7)

PDB	External Database	Details
Gly 238	Ala 238	conflict

AY: 1 - 378 (UniProt: C9ZK52)

PDB	External Database	Details
Glu 345	Val 345	conflict

Ab: 1 - 507 (UniProt: Q381T7)

PDB	External Database	Details
Ser 290	Phe 290	conflict
Glu 299	Lys 299	conflict
Asn 471	Ile 471	conflict

Ap: 1 - 309 (UniProt: Q57YA9)

PDB	External Database	Details
Leu 2	Ser 2	conflict

Av: 1 - 242 (UniProt: Q383B7)

PDB	External Database	Details
Arg 164	Gln 164	conflict

AA: 1 - 1178 (GenBank: 343546)

PDB	External Database	Details
A 448	U 1811	conflict
A 622	U 1985	conflict
A 636	G 1999	conflict
G 702	A 2065	conflict
C 706	U 2069	conflict
C 743	G 2106	conflict
G 752	A 2115	conflict
U 757	A 2120	conflict
U 760	G 2123	conflict
U 762	G 2125	conflict
G 789	C 2152	conflict
G 793	U 2156	conflict
A 875	G 2238	conflict
G 876	A 2239	conflict
A 877	G 2240	conflict

BC: 1 - 523 (UniProt: Q584V5)

PDB	External Database	Details
Pro 29	Ser 29	conflict
Gly 42	Ser 42	conflict

BF: 1 - 426 (UniProt: C9ZR63)

PDB	External Database	Details
Ile 296	Thr 296	conflict

BG: 1 - 378 (UniProt: Q57Y49)

PDB	External Database	Details
Phe 185	Leu 185	conflict

BI: 1 - 342 (UniProt: Q38CK0)

PDB	External Database	Details
Asn 227	Asp 227	conflict
Arg 319	Gln 319	conflict
Ala 343	-	expression tag

BJ: 1 - 333 (UniProt: Q383M2)

PDB	External Database	Details
Glu 329	Ala 329	conflict

BK: 1 - 386 (UniProt: C9ZQR6)

PDB	External Database	Details
Val 348	Leu 348	conflict

BN: -43 - 258 (UniProt: Q585A3)

PDB	External Database	Details
Thr 145	Ala 189	conflict

BS: 1 - 198 (UniProt: Q38FG8)

PDB	External Database	Details
Ile 45	Val 45	conflict
Unk 173	Leu 173	conflict

BT: 1 - 191 (UniProt: C9ZPU8)

PDB	External Database	Details
Arg 70	Gln 70	conflict

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	91
Polymers	Total formula weight	2559193.6
Non-Polymers*	Number of molecules	14
Non-Polymers*	Total formula weight	1226.0
All*	Total formula weight	2560419.6

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)