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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6HIW

Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete small mitoribosomal subunit in complex with mt-IF-3

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(DA)		mS48polymer1788201811.21UniProt (Q57UJ2)Trypanosoma brucei brucei
2B
(DD)		mS51polymer81295081.01UniProt (Q385L8)Trypanosoma brucei brucei
3C
(DI)		mS56polymer40747306.81UniProt (Q587C2)Trypanosoma brucei brucei
4D
(DL)		mS59polymer30735395.71UniProt (Q38BS2)Trypanosoma brucei brucei
5E
(DM)		mS60polymer29434546.61UniProt (Q57XL2)Trypanosoma brucei brucei
6F
(DN)		mS61polymer29333482.31UniProt (Q38D60)Trypanosoma brucei brucei
7G
(DO)		mS62polymer28232068.11UniProt (Q383D1)Trypanosoma brucei brucei
8H
(DP)		mS63polymer27431922.21UniProt (Q38F25)Trypanosoma brucei brucei
9I
(DQ)		mS64polymer26830742.21UniProt (Q382E8)
Pfam (PF10469)		Trypanosoma brucei brucei
10J
(DR)		mS65polymer27030617.41UniProt (Q57UA2)Trypanosoma brucei brucei
11K
(DS)		mS66polymer26129960.21UniProt (Q388L7)
Pfam (PF14311)		Trypanosoma brucei brucei
12L
(DU)		mS68polymer22826472.81UniProt (Q582T9)
Pfam (PF00240)		Trypanosoma brucei brucei
13M
(DZ)		mS73polymer9411360.91UniProt (Q587C4)Trypanosoma brucei brucei
14N
(Da)		mS74polymer648203.41Trypanosoma brucei brucei
15O
(DB)		mS49polymer1181137234.11UniProt (Q586P5)Trypanosoma brucei brucei
16P
(DC)		mS50polymer1165131719.31UniProt (Q57YB5)Trypanosoma brucei brucei
17Q
(DE)		mS52polymer74785012.31UniProt (Q386Q7)Trypanosoma brucei brucei
18R
(DF)		mS53polymer66675338.91UniProt (Q38ET1)Trypanosoma brucei brucei
19S
(DG)		mS54polymer63172046.01UniProt (Q57ZP8)Trypanosoma brucei brucei
20T
(DH)		mS55polymer58166676.71UniProt (Q580V1)Trypanosoma brucei brucei
21U
(DJ)		mS57polymer39645956.31UniProt (Q584U8)Trypanosoma brucei brucei
22V
(DK)		mS58polymer32435623.91UniProt (Q38BP1)Trypanosoma brucei brucei
23W
(DT)		mS67polymer24730096.11UniProt (Q586G5)
Pfam (PF00581)		Trypanosoma brucei brucei
24X
(DV)		mS69polymer18321589.71UniProt (Q57UZ6)Trypanosoma brucei brucei
25Y
(DW)		mS70polymer17921247.41UniProt (Q383N9)Trypanosoma brucei brucei
26Z
(DX)		mS71polymer16920093.21UniProt (Q383G5)Trypanosoma brucei brucei
27AA
(DY)		mS72polymer16319317.31UniProt (Q57YD4)Trypanosoma brucei brucei
28BA
(CC)		uS3mpolymer749070.91Trypanosoma brucei brucei
29CA
(CE)		uS5mpolymer43550147.41UniProt (Q38AX6)
Pfam (PF03719)		Trypanosoma brucei brucei
30DA
(CF)		bS6mpolymer16018861.51UniProt (Q38BW5)Trypanosoma brucei brucei
31EA
(CH)		uS8mpolymer28232766.51UniProt (Q388R7)
Pfam (PF00410)		Trypanosoma brucei brucei
32FA
(CI)		uS9mpolymer44350201.01UniProt (Q57W62)
Pfam (PF00380)		Trypanosoma brucei brucei
33GA
(CJ)		uS10mpolymer81794351.01UniProt (Q57Z45)
Pfam (PF01476)		Trypanosoma brucei brucei
34HA
(CK)		uS11mpolymer32637925.91UniProt (Q389T7)Trypanosoma brucei brucei
35IA
(CL)		uS12mpolymer8710421.61Trypanosoma brucei brucei
36JA
(CN)		uS14mpolymer16619900.01UniProt (Q580I0)Trypanosoma brucei brucei
37KA
(CO)		uS15mpolymer42950401.21UniProt (Q4GZ99)Trypanosoma brucei brucei
38LA
(CP)		bS16mpolymer18822077.81UniProt (Q384N9)Trypanosoma brucei brucei
39MA
(CQ)		uS17mpolymer30735632.71UniProt (Q38DP8)
Pfam (PF00366)		Trypanosoma brucei brucei
40NA
(CR)		bS18mpolymer32036988.71UniProt (Q38AS2)Trypanosoma brucei brucei
41OA
(CS)		uS19mpolymer24428364.61UniProt (Q584T8)Trypanosoma brucei brucei
42PA
(CU)		bS21mpolymer19323087.91UniProt (Q580M9)Trypanosoma brucei brucei
43QA
(CZ)		mt-IF-3polymer36041086.31UniProt (Q57WU2)Trypanosoma brucei brucei
44RA
(Ca)		mS22polymer60273064.11UniProt (Q38DR3)Trypanosoma brucei brucei
45SA
(Cb)		mS23polymer32536855.61UniProt (Q57VB2)Trypanosoma brucei brucei
46TA
(Cd)		mS26polymer44051164.71UniProt (Q38DK6)Trypanosoma brucei brucei
47UA
(Cg)		mS29polymer49857048.81UniProt (Q585C2)
Pfam (PF10236)		Trypanosoma brucei brucei
48VA
(Ci)		mS33polymer18121244.11UniProt (Q57WW0)Trypanosoma brucei brucei
49WA
(Cj)		mS34polymer25728728.21UniProt (Q57UK0)Trypanosoma brucei brucei
50XA
(Ck)		mS35polymer87498377.81UniProt (Q387C7)Trypanosoma brucei brucei
51YA
(Cm)		mS37polymer21524757.91UniProt (Q38C96)Trypanosoma brucei brucei
52ZA
(Cn)		mS38polymer25028240.61UniProt (Q57VQ9)Trypanosoma brucei brucei
53AB
(Cp)		mS41polymer18722421.51UniProt (Q389L3)
Pfam (PF09597)		Trypanosoma brucei brucei
54BB
(Cq)		mS42polymer26329748.71UniProt (Q586A1)
Pfam (PF02777)		Trypanosoma brucei brucei
55CB
(Cr)		mS43polymer43948590.41UniProt (Q585I1)
Pfam (PF02777)		Trypanosoma brucei brucei
56DB
(Cv)		mS47polymer1211137929.01UniProt (Q383R4)
Pfam (PF16113)		Trypanosoma brucei brucei
57EB
(CA)		9S rRNApolymer621198442.41GenBank (343546)Trypanosoma brucei brucei
58FB
(UO)		Unknown Proteinpolymer5443.51Trypanosoma brucei brucei
59GB
(UP)		Unknown Proteinpolymer7613.71Trypanosoma brucei brucei
60HB
(UQ)		Unknown Proteinpolymer322741.41Trypanosoma brucei brucei
61IB
(UR)		Unknown Proteinpolymer8698.91Trypanosoma brucei brucei
62JB
(US)		Unknown Proteinpolymer544613.71Trypanosoma brucei brucei
63KB
(UT)		Unknown Proteinpolymer443762.61Trypanosoma brucei brucei
64LB, MB, NB, TB
(DA, DS, Cr)		ZINC IONnon-polymer65.44Chemie (ZN)
65OB
(DJ)		URIDINE 5'-TRIPHOSPHATEnon-polymer484.11Chemie (UTP)
66AC, AD, BC, BD, CC...
(CA, CQ, Ca, Cg, Cv)		MAGNESIUM IONnon-polymer24.339Chemie (MG)
67RB
(Cg)		GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
68ED, FD, GD, HD
(CA)		SPERMIDINEnon-polymer145.24Chemie (SPD)
69ID
(CA)		SPERMINEnon-polymer202.31Chemie (SPM)
70JD
(Cg)		waterwater18.03Chemie (HOH)
Sequence modifications
DA: 1 - 1788 (UniProt: Q57UJ2)
PDBExternal DatabaseDetails
His 894Asn 894conflict
Thr 1181Ile 1181conflict
Ala 1333Val 1333conflict
Arg 1700His 1700conflict
Lys 1761Arg 1761conflict
DD: 1 - 812 (UniProt: Q385L8)
PDBExternal DatabaseDetails
Pro 371Ser 371conflict
Ala 599Val 599conflict
DI: 1 - 407 (UniProt: Q587C2)
PDBExternal DatabaseDetails
Glu 92Gly 92conflict
Asp 116Glu 116conflict
DL: 1 - 307 (UniProt: Q38BS2)
PDBExternal DatabaseDetails
Thr 274Ala 274conflict
DM: 1 - 294 (UniProt: Q57XL2)
PDBExternal DatabaseDetails
Phe 69Tyr 69conflict
Asn 97Ser 97conflict
Ser 138Pro 138conflict
Ala 173Thr 173conflict
Ala 206Thr 206conflict
DN: 1 - 293 (UniProt: Q38D60)
PDBExternal DatabaseDetails
Gly 51Ser 51conflict
DP: 1 - 274 (UniProt: Q38F25)
PDBExternal DatabaseDetails
His 3Arg 3conflict
DR: 1 - 270 (UniProt: Q57UA2)
PDBExternal DatabaseDetails
Gly 65Ser 65conflict
Gly 94Glu 94conflict
Pro 128Ser 128conflict
Arg 229Gln 229conflict
DU: 1 - 228 (UniProt: Q582T9)
PDBExternal DatabaseDetails
Ile 119Leu 119conflict
Ile 152Val 152conflict
DB: 1 - 1181 (UniProt: Q586P5)
PDBExternal DatabaseDetails
Val 23Ala 23conflict
Ile 359Thr 359conflict
Gln 384His 384conflict
Thr 402Ile 402conflict
Thr 423Ala 423conflict
Arg 586His 586conflict
Arg 593Lys 593conflict
Ser 647Gly 647conflict
DC: 1 - 1165 (UniProt: Q57YB5)
PDBExternal DatabaseDetails
Ala 53Thr 53conflict
Lys 365Glu 365conflict
Thr 385Ala 385conflict
Ile 405Val 405conflict
Ser 641Pro 641conflict
Lys 651Glu 651conflict
Glu 731Asp 731conflict
Gln 814His 814conflict
Ala 1097Val 1097conflict
Thr 1113Ile 1113conflict
DE: 1 - 747 (UniProt: Q386Q7)
PDBExternal DatabaseDetails
Thr 514Ser 514conflict
DF: 1 - 666 (UniProt: Q38ET1)
PDBExternal DatabaseDetails
Thr 18Ala 18conflict
Asp 258Asn 258conflict
Asn 372Asp 372conflict
Asn 406Ser 406conflict
Asp 510Gly 510conflict
Ala 577Val 577conflict
Unk 636Gly 636conflict
Lys 638Arg 638conflict
DG: 1 - 631 (UniProt: Q57ZP8)
PDBExternal DatabaseDetails
Asn 428Ser 428conflict
Gly 429Ser 429conflict
DH: 1 - 581 (UniProt: Q580V1)
PDBExternal DatabaseDetails
His 191Gln 191conflict
Pro 194Arg 194conflict
Gly 488Ser 488conflict
DK: 1 - 324 (UniProt: Q38BP1)
PDBExternal DatabaseDetails
Ser 61Pro 131conflict
Gly 257Ser 327conflict
DV: 1 - 183 (UniProt: Q57UZ6)
PDBExternal DatabaseDetails
Ala 163Thr 163conflict
DW: 1 - 179 (UniProt: Q383N9)
PDBExternal DatabaseDetails
Thr 74Met 74conflict
CE: 1 - 435 (UniProt: Q38AX6)
PDBExternal DatabaseDetails
Arg 341Lys 341conflict
CH: 1 - 282 (UniProt: Q388R7)
PDBExternal DatabaseDetails
Asn 74Ser 74conflict
CI: 1 - 443 (UniProt: Q57W62)
PDBExternal DatabaseDetails
Ala 370Val 370conflict
CJ: 1 - 817 (UniProt: Q57Z45)
PDBExternal DatabaseDetails
Leu 311Tyr 311conflict
His 484Arg 484conflict
Ser 488Asn 488conflict
Glu 594Val 594conflict
Arg 629Lys 629conflict
CK: 1 - 326 (UniProt: Q389T7)
PDBExternal DatabaseDetails
Arg 3Gln 3conflict
Unk 138Ile 138conflict
CQ: 1 - 307 (UniProt: Q38DP8)
PDBExternal DatabaseDetails
Ala 138Val 138conflict
CR: 1 - 320 (UniProt: Q38AS2)
PDBExternal DatabaseDetails
Ile 8Val 8conflict
CS: 1 - 172 (UniProt: Q584T8)
PDBExternal DatabaseDetails
Met -71-initiating methionine
Ala -70-expression tag
Phe -69-expression tag
Arg -68-expression tag
Asn -67-expression tag
Thr -66-expression tag
Phe -65-expression tag
Thr -64-expression tag
Thr -63-expression tag
Pro -62-expression tag
Gly -61-expression tag
Lys -60-expression tag
Phe -59-expression tag
Ser -58-expression tag
Thr -57-expression tag
Val -56-expression tag
Ser -55-expression tag
Lys -54-expression tag
Asn -53-expression tag
Ile -52-expression tag
Val -51-expression tag
Leu -50-expression tag
Leu -49-expression tag
Leu -48-expression tag
Ile -47-expression tag
Trp -46-expression tag
Arg -45-expression tag
Val -44-expression tag
Lys -43-expression tag
Val -42-expression tag
Phe -41-expression tag
Leu -40-expression tag
Arg -39-expression tag
Ala -38-expression tag
Glu -37-expression tag
Gly -36-expression tag
Phe -35-expression tag
Ala -34-expression tag
His -33-expression tag
Ser -32-expression tag
Leu -31-expression tag
Val -30-expression tag
Met -29-expression tag
Leu -28-expression tag
Pro -27-expression tag
Val -26-expression tag
Ser -25-expression tag
Leu -24-expression tag
Tyr -23-expression tag
Ser -22-expression tag
Lys -21-expression tag
Ile -20-expression tag
Leu -19-expression tag
Leu -18-expression tag
Cys -17-expression tag
Asp -16-expression tag
Val -15-expression tag
Lys -14-expression tag
Lys -13-expression tag
Lys -12-expression tag
Ile -11-expression tag
Val -10-expression tag
Tyr -9-expression tag
Phe -8-expression tag
His -7-expression tag
Cys -6-expression tag
Cys -5-expression tag
Thr -4-expression tag
Arg -3-expression tag
Lys -2-expression tag
Lys -1-expression tag
Ser 0-expression tag
CZ: 1 - 360 (UniProt: Q57WU2)
PDBExternal DatabaseDetails
Ser 6Gly 6conflict
Thr 30Ile 30conflict
Thr 172Ala 172conflict
Cb: 1 - 311 (UniProt: Q57VB2)
PDBExternal DatabaseDetails
Ser 244Asn 244conflict
-Glu 246deletion
Ala 312-expression tag
Cys 313-expression tag
Ser 314-expression tag
Arg 315-expression tag
Asp 316-expression tag
Gly 317-expression tag
Phe 318-expression tag
Ala 319-expression tag
Leu 320-expression tag
Met 321-expression tag
Lys 322-expression tag
Ala 323-expression tag
Asn 324-expression tag
Lys 325-expression tag
Cd: 1 - 440 (UniProt: Q38DK6)
PDBExternal DatabaseDetails
Unk 299Gly 299conflict
Cg: 1 - 497 (UniProt: Q585C2)
PDBExternal DatabaseDetails
Val 181Ala 181conflict
Arg 498-expression tag
Ck: 1 - 874 (UniProt: Q387C7)
PDBExternal DatabaseDetails
Ser 107Leu 107conflict
Phe 144Leu 144conflict
Tyr 253Phe 253conflict
Glu 339Val 339conflict
Gly 871Glu 871conflict
Cq: 1 - 263 (UniProt: Q586A1)
PDBExternal DatabaseDetails
Thr 48Ala 48conflict
Met 167Val 167conflict
Cr: 1 - 439 (UniProt: Q585I1)
PDBExternal DatabaseDetails
Lys 351Glu 351conflict
Cv: 1 - 1211 (UniProt: Q383R4)
PDBExternal DatabaseDetails
Thr 718Ala 718conflict
Glu 1179Gly 1179conflict
CA: 1 - 613 (GenBank: 343546)
PDBExternal DatabaseDetails
U 298C 2839conflict
U 473G 3014conflict
U 614-insertion
U 615-insertion
U 616-insertion
U 617-insertion
U 618-insertion
U 619-insertion
U 620-insertion
U 621-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains63
Total formula weight2841694.7
Non-Polymers*Number of molecules50
Total formula weight3000.2
All*Total formula weight2844694.8
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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