6HI2
PI3 Kinase Delta in complex with 3{6[(1S,6R)3oxabicyclo[4.1.0]heptan6yl]pyridin2yl}phenol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | polymer | 940 | 107823.7 | 1 | UniProt (O35904) Pfam (PF00794) Pfam (PF00792) Pfam (PF00613) Pfam (PF00454) In PDB | Mus musculus (Mouse) | PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,p110delta |
| 2 | A | 3-[6-[(1~{S},6~{R})-3-oxabicyclo[4.1.0]heptan-6-yl]pyridin-2-yl]phenol | non-polymer | 267.3 | 1 | Chemie (G62) | |||
| 3 | water | water | 18.0 | 615 | Chemie (HOH) |
Sequence modifications
A: 105 - 1044 (UniProt: O35904)
| PDB | External Database | Details |
|---|---|---|
| Gly 105 | Glu 105 | conflict |
| Gln 508 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 107823.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 267.3 | |
| All* | Total formula weight | 108091.0 |
