6HH6
Human poly(ADP-ribose) glycohydrolase in complex with ADP-HPM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly(ADP-ribose) glycohydrolase | polymer | 531 | 60944.3 | 1 | UniProt (Q86W56) Pfam (PF20811) Pfam (PF05028) In PDB | Homo sapiens (Human) | |
| 2 | A | Adenosine Diphosphate (Hydroxymethyl)pyrrolidine monoalcohol | non-polymer | 526.3 | 1 | Chemie (A3R) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 503 | Chemie (HOH) |
Sequence modifications
A: 448 - 976 (UniProt: Q86W56)
| PDB | External Database | Details |
|---|---|---|
| Gly 446 | - | expression tag |
| Ser 447 | - | expression tag |
| Ala 616 | Lys 508 | engineered mutation |
| Ala 617 | Gln 509 | engineered mutation |
| Ala 618 | Lys 510 | engineered mutation |
| Ala 688 | Glu 580 | engineered mutation |
| Ala 689 | Lys 581 | engineered mutation |
| Ala 690 | Lys 582 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60944.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 910.6 | |
| All* | Total formula weight | 61854.8 |
