6HDR
Human DYRK2 bound to Curcumin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | polymer | 429 | 49600.9 | 1 | UniProt (Q92630) Pfam (PF00069) | Homo sapiens (Human) | |
| 2 | B (A) | curcumin | non-polymer | 368.4 | 1 | Chemie (CC9) | |||
| 3 | C (A) | DITHIANE DIOL | non-polymer | 152.2 | 1 | Chemie (DTD) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 73 - 479 (UniProt: Q92630)
| PDB | External Database | Details |
|---|---|---|
| Met 51 | - | initiating methionine |
| His 52 | - | expression tag |
| His 53 | - | expression tag |
| His 54 | - | expression tag |
| His 55 | - | expression tag |
| His 56 | - | expression tag |
| His 57 | - | expression tag |
| Ser 58 | - | expression tag |
| Sep 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Val 61 | - | expression tag |
| Asp 62 | - | expression tag |
| Leu 63 | - | expression tag |
| Gly 64 | - | expression tag |
| Thr 65 | - | expression tag |
| Glu 66 | - | expression tag |
| Asn 67 | - | expression tag |
| Leu 68 | - | expression tag |
| Tyr 69 | - | expression tag |
| Phe 70 | - | expression tag |
| Gln 71 | - | expression tag |
| Ser 72 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49600.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 615.6 | |
| All* | Total formula weight | 50216.5 |
