6HDP

Human DYRK2 bound to Scorzodihydrostilbene A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Dual specificity tyrosine-phosphorylation-regulated kinase 2	polymer	429	49520.9	1	UniProt (Q92630) Pfam (PF00069)	Homo sapiens (Human)
2	B (A)	Scorzodihydrostilbene A	non-polymer		464.5	1	Chemie (FZ5)
3	C (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	D (A)	water	water		18.0	164	Chemie (HOH)

Sequence modifications

A: 73 - 479 (UniProt: Q92630)

PDB	External Database	Details
Met 51	-	initiating methionine
His 52	-	expression tag
His 53	-	expression tag
His 54	-	expression tag
His 55	-	expression tag
His 56	-	expression tag
His 57	-	expression tag
Ser 58	-	expression tag
Ser 59	-	expression tag
Gly 60	-	expression tag
Val 61	-	expression tag
Asp 62	-	expression tag
Leu 63	-	expression tag
Gly 64	-	expression tag
Thr 65	-	expression tag
Glu 66	-	expression tag
Asn 67	-	expression tag
Leu 68	-	expression tag
Tyr 69	-	expression tag
Phe 70	-	expression tag
Gln 71	-	expression tag
Ser 72	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	49520.9
Non-Polymers*	Number of molecules	2
	Total formula weight	487.5
All*	Total formula weight	50008.4

*Water molecules are not included.