6HD7

Cryo-EM structure of the ribosome-NatA complex

This is a large structure.

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNApolymer33961097493.91
REF (831416132)
Saccharomyces cerevisiae
35S rRNApolymer12138951.11
Saccharomyces cerevisiae
45.8S rRNApolymer15850682.91
GenBank (MH459411.1)
Saccharomyces cerevisiae
AtRNApolymer7624378.41
Saccharomyces cerevisiae
BP-site tRNApolymer7724815.71
Saccharomyces cerevisiae
C60S ribosomal protein L42-Apolymer10612246.71
UniProt (P0CX27)
Pfam (PF00935)
Saccharomyces cerevisiaeL41,Large ribosomal subunit protein eL42-A,YL27,YP44
D60S ribosomal protein L43-Apolymer9210113.01
UniProt (P0CX25)
Pfam (PF01780)
Saccharomyces cerevisiaeL37a,Large ribosomal subunit protein eL43-A,YL35
E60S ribosomal protein L2-Apolymer25427463.61
UniProt (P0CX45)
Pfam (PF00181)
Pfam (PF03947)
Saccharomyces cerevisiaeL5,Large ribosomal subunit protein uL2-A,RP8,YL6
F60S ribosomal protein L3polymer38743850.81
UniProt (P14126)
Pfam (PF00297)
Saccharomyces cerevisiaeLarge ribosomal subunit protein uL3,Maintenance of killer protein 8,RP1,Trichodermin resistance protein,YL1
G60S ribosomal protein L4-Apolymer36239159.11
UniProt (P10664)
Pfam (PF00573)
Pfam (PF14374)
Saccharomyces cerevisiaeL2,Large ribosomal subunit protein uL4-A,RP2,YL2
H60S ribosomal protein L5polymer29733764.81
UniProt (P26321)
Pfam (PF14204)
Pfam (PF17144)
Saccharomyces cerevisiaeL1,L1a,Large ribosomal subunit protein uL18,Ribosomal 5S RNA-binding protein,YL3
I60S ribosomal protein L6-Apolymer17620000.61
UniProt (Q02326)
Pfam (PF01159)
Saccharomyces cerevisiaeL17,Large ribosomal subunit protein eL6-A,RP18,YL16
J60S ribosomal protein L7-Apolymer24427686.31
UniProt (P05737)
Pfam (PF00327)
Pfam (PF08079)
Saccharomyces cerevisiaeL6,Large ribosomal subunit protein uL30-A,RP11,YL8
K60S ribosomal protein L8-Apolymer25628175.81
UniProt (P17076)
Pfam (PF01248)
Saccharomyces cerevisiaeL4,L4-2,L7a-1,Large ribosomal subunit protein eL8-A,Maintenance of killer protein 7,RP6,YL5
L60S ribosomal protein L9-Apolymer19121605.11
UniProt (P05738)
Pfam (PF00347)
Saccharomyces cerevisiaeL8,Large ribosomal subunit protein uL6-A,RP24,YL11
M60S ribosomal protein L11-Apolymer17419755.71
UniProt (P0C0W9)
Pfam (PF00281)
Pfam (PF00673)
Saccharomyces cerevisiaeL16,Large ribosomal subunit protein uL5-A,RP39,YL22
N60S ribosomal protein L13-Apolymer19922604.21
UniProt (Q12690)
Pfam (PF01294)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL13-A
O60S ribosomal protein L14-Apolymer13815195.11
UniProt (P36105)
Pfam (PF01929)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL14-A
P60S ribosomal protein L15-Apolymer20424482.41
UniProt (P05748)
Pfam (PF00827)
Saccharomyces cerevisiaeL13,Large ribosomal subunit protein eL15-A,RP15R,YL10,YP18
Q60S ribosomal protein L16-Apolymer19922247.21
UniProt (P26784)
Pfam (PF00572)
Saccharomyces cerevisiaeL13a,L21,Large ribosomal subunit protein uL13-A,RP22,YL15
R60S ribosomal protein L17-Apolymer18420589.51
UniProt (P05740)
Pfam (PF00237)
Saccharomyces cerevisiaeL20A,Large ribosomal subunit protein uL22-A,YL17
S60S ribosomal protein L18-Apolymer18620609.31
UniProt (P0CX49)
Pfam (PF17135)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL18-A,RP28
T60S ribosomal protein L19-Apolymer18921762.31
UniProt (P0CX82)
Pfam (PF01280)
Saccharomyces cerevisiaeL23,Large ribosomal subunit protein eL19-A,RP15L,RP33,YL14
U60S ribosomal protein L20-Apolymer17220478.91
UniProt (P0CX23)
Pfam (PF01775)
Saccharomyces cerevisiaeL18a,Large ribosomal subunit protein eL20-A
V60S ribosomal protein L21-Apolymer16018279.31
UniProt (Q02753)
Pfam (PF01157)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL21-A
W60S ribosomal protein L22-Apolymer12113711.41
UniProt (P05749)
Pfam (PF01776)
Saccharomyces cerevisiaeL1c,Large ribosomal subunit protein eL22-A,RP4,YL31
X60S ribosomal protein L23-Apolymer13714494.01
UniProt (P0CX41)
Pfam (PF00238)
Saccharomyces cerevisiaeL17a,Large ribosomal subunit protein uL14-A,YL32
Y60S ribosomal protein L24-Apolymer15517661.71
UniProt (P04449)
Pfam (PF01246)
Saccharomyces cerevisiaeL30,Large ribosomal subunit protein eL24-A,RP29,YL21
Z60S ribosomal protein L25polymer14215787.61
UniProt (P04456)
Pfam (PF00276)
Pfam (PF03939)
Saccharomyces cerevisiaeLarge ribosomal subunit protein uL23,RP16L,YL25,YP42'
a60S ribosomal protein L26-Apolymer12714265.81
UniProt (P05743)
Pfam (PF00467)
Pfam (PF16906)
Saccharomyces cerevisiaeL33,Large ribosomal subunit protein uL24-A,YL33
b60S ribosomal protein L27-Apolymer13615568.41
UniProt (P0C2H6)
Pfam (PF01777)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL27-A
c60S ribosomal protein L28polymer14916761.71
UniProt (P02406)
Pfam (PF00828)
Saccharomyces cerevisiaeL27a,L29,Large ribosomal subunit protein uL15,RP44,RP62,YL24
d60S ribosomal protein L29polymer596691.91
UniProt (P05747)
Pfam (PF01779)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL29,YL43
e60S ribosomal protein L30polymer10511430.41
UniProt (P14120)
Pfam (PF01248)
Saccharomyces cerevisiaeL32,Large ribosomal subunit protein eL30,RP73,YL38
f60S ribosomal protein L31-Apolymer10912649.81
UniProt (P0C2H8)
Pfam (PF01198)
Saccharomyces cerevisiaeL34,Large ribosomal subunit protein eL31-A,YL28
g60S ribosomal protein L32polymer13014809.41
UniProt (P38061)
Pfam (PF01655)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL32
h60S ribosomal protein L33-Apolymer10712177.11
UniProt (P05744)
Pfam (PF01247)
Saccharomyces cerevisiaeL37,Large ribosomal subunit protein eL33-A,RP47,YL37
i60S ribosomal protein L34-Apolymer12113673.21
UniProt (P87262)
Pfam (PF01199)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL34-A
j60S ribosomal protein L35-Apolymer12013942.61
UniProt (P0CX84)
Pfam (PF00831)
Saccharomyces cerevisiaeLarge ribosomal subunit protein uL29-A
k60S ribosomal protein L36-Apolymer10011151.31
UniProt (P05745)
Pfam (PF01158)
Saccharomyces cerevisiaeL39,Large ribosomal subunit protein eL36-A,YL39
l60S ribosomal protein L37-Apolymer889877.41
UniProt (P49166)
Pfam (PF01907)
Saccharomyces cerevisiaeL43,Large ribosomal subunit protein eL37-A,YL35,YP55
m60S ribosomal protein L38polymer788845.61
UniProt (P49167)
Pfam (PF01781)
Saccharomyces cerevisiaeLarge ribosomal subunit protein eL38
n60S ribosomal protein L39polymer516358.61
UniProt (P04650)
Pfam (PF00832)
Saccharomyces cerevisiaeL46,Large ribosomal subunit protein eL39,YL40
oUbiquitin-60S ribosomal protein L40polymer12814583.11
UniProt (P0CH08)
Pfam (PF00240)
Pfam (PF01020)
Saccharomyces cerevisiae
p60S ribosomal protein L41-Apolymer253354.21
Saccharomyces cerevisiae
rribosomal protein RPL1polymer21017890.01
Saccharomyces cerevisiae
s60S ribosomal protein L10polymer22125410.51
UniProt (P41805)
Pfam (PF00252)
Saccharomyces cerevisiaeL9,Large ribosomal subunit protein uL16,Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein
tN-terminal acetyltransferase A complex subunit NAT1polymer85499050.11
UniProt (P12945)
Pfam (PF12569)
Saccharomyces cerevisiaeNatA complex subunit NAT1,Amino-terminal,alpha-amino,acetyltransferase 1
uN-terminal acetyltransferase A complex catalytic subunit ARD1polymer23827635.21
UniProt (P07347)
Pfam (PF00583)
Saccharomyces cerevisiaeNatA complex subunit ARD1,Arrest-defective protein 1
vN-alpha-acetyltransferase NAT5polymer17619753.71
UniProt (Q08689)
Pfam (PF00583)
Saccharomyces cerevisiaeNatA complex subunit NAT5
znascent polypeptide chainpolymer231975.41
Saccharomyces cerevisiae
4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dionenon-polymer281.31

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains51
Total molecular weight2145901.3
Non-Polymers*Number of molecules1
Total molecular weight281.3
All*Total molecular weight2146182.7
*Water molecules are not included.
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