6HCU
Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum bound to a difluoro cyclohexyl chromone ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine--tRNA ligase | polymer | 507 | 58706.9 | 2 | UniProt (Q8IDJ8) Pfam (PF01336) Pfam (PF00152) | Plasmodium falciparum 3D7 | Lysyl-tRNA synthetase |
| 2 | C, I (A, B) | ~{N}-[[4,4-bis(fluoranyl)-1-oxidanyl-cyclohexyl]methyl]-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide | non-polymer | 355.3 | 2 | Chemie (FYB) | |||
| 3 | D (A) | LYSINE | non-polymer | 147.2 | 1 | Chemie (LYS) | |||
| 4 | E (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | F (A) | HISTIDINE | non-polymer | 156.2 | 1 | Chemie (HIS) | |||
| 6 | G, H, J, K (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 4 | Chemie (TRS) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 966 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 117413.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1608.7 | |
| All* | Total formula weight | 119022.5 |
