6HC2

Crystal structure of NuMA/LGN hetero-hexamers

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I...	G-protein-signaling modulator 2	polymer	367	40755.6	12	UniProt (P81274) Pfam (PF13374) Pfam (PF13176) Pfam (PF13181) In PDB	Homo sapiens (Human)	Mosaic protein LGN
2	B, D, F, H, J...	Nuclear mitotic apparatus protein 1	polymer	71	7747.4	12	UniProt (Q14980) In PDB	Homo sapiens (Human)	Nuclear matrix protein-22,NMP-22,Nuclear mitotic apparatus protein,NuMA protein,SP-H antigen

Sequence modifications

A, C, E, G, I, K, M, O, Q, S, U, W: 7 - 367 (UniProt: P81274)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Leu 3	-	expression tag
Gly 4	-	expression tag
Ser 5	-	expression tag
Met 6	-	expression tag

B, D, F, H, J, L, N, P, R, T, V, X: 1860 - 1928 (UniProt: Q14980)

PDB	External Database	Details
Gly 1858	-	expression tag
Pro 1859	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	24
	Total formula weight	582036.5
All*	Total formula weight	582036.5

*Water molecules are not included.