6HAZ
Crystal structure of the bromodomain of human SMARCA2 in complex with SMARCA-BD ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Probable global transcription activator SNF2L2 | polymer | 123 | 14380.5 | 2 | UniProt (P51531) Pfam (PF00439) In PDB | Homo sapiens (Human) | ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
| 2 | A, B | 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl)phenol | non-polymer | 272.3 | 2 | Chemie (FX5) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, B: 1373 - 1493 (UniProt: P51531)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28761.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 675.5 | |
| All* | Total formula weight | 29436.6 |
