6HA1
Cryo-EM structure of a 70S Bacillus subtilis ribosome translating the ErmD leader peptide in complex with telithromycin
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 23S ribosomal RNA | polymer | 2928 | 949646.3 | 1 | GenBank (467326) | Bacillus subtilis (strain 168) | |
| 2 | B (B) | 5S ribosomal RNA | polymer | 112 | 36157.5 | 1 | GenBank (1150402534) | Bacillus subtilis (strain 168) | |
| 3 | C (C) | 50S ribosomal protein L2 | polymer | 277 | 30335.1 | 1 | UniProt (P42919) Pfam (PF00181) Pfam (PF03947) | Bacillus subtilis (strain 168) | BL2 |
| 4 | D (D) | 50S ribosomal protein L3 | polymer | 209 | 22723.3 | 1 | UniProt (P42920) Pfam (PF00297) | Bacillus subtilis (strain 168) | BL3 |
| 5 | E (E) | 50S ribosomal protein L4 | polymer | 207 | 22425.0 | 1 | UniProt (P42921) Pfam (PF00573) | Bacillus subtilis (strain 168) | |
| 6 | F (F) | 50S ribosomal protein L5 | polymer | 179 | 20177.6 | 1 | UniProt (P12877) Pfam (PF00281) Pfam (PF00673) | Bacillus subtilis (strain 168) | BL6 |
| 7 | G (G) | 50S ribosomal protein L6 | polymer | 179 | 19543.4 | 1 | UniProt (P46898) Pfam (PF00347) | Bacillus subtilis (strain 168) | BL10 |
| 8 | H (J) | 50S ribosomal protein L13 | polymer | 145 | 16407.1 | 1 | UniProt (P70974) Pfam (PF00572) | Bacillus subtilis (strain 168) | |
| 9 | I (K) | 50S ribosomal protein L14 | polymer | 122 | 13175.3 | 1 | UniProt (P12875) Pfam (PF00238) | Bacillus subtilis (strain 168) | |
| 10 | J (L) | 50S ribosomal protein L15 | polymer | 146 | 15410.7 | 1 | UniProt (P19946) Pfam (PF00828) | Bacillus subtilis (strain 168) | |
| 11 | K (M) | 50S ribosomal protein L16 | polymer | 144 | 16223.0 | 1 | UniProt (P14577) Pfam (PF00252) | Bacillus subtilis (strain 168) | |
| 12 | L (N) | 50S ribosomal protein L17 | polymer | 120 | 13774.8 | 1 | UniProt (P20277) Pfam (PF01196) | Bacillus subtilis (strain 168) | BL15,BL21 |
| 13 | M (O) | 50S ribosomal protein L18 | polymer | 120 | 12993.8 | 1 | UniProt (P46899) Pfam (PF00861) | Bacillus subtilis (strain 168) | BL16 |
| 14 | N (P) | 50S ribosomal protein L19 | polymer | 115 | 13416.9 | 1 | UniProt (O31742) Pfam (PF01245) | Bacillus subtilis (strain 168) | |
| 15 | O (Q) | 50S ribosomal protein L20 | polymer | 119 | 13669.2 | 1 | UniProt (P55873) Pfam (PF00453) | Bacillus subtilis (strain 168) | |
| 16 | P (R) | 50S ribosomal protein L21 | polymer | 102 | 11296.1 | 1 | UniProt (P26908) Pfam (PF00829) | Bacillus subtilis (strain 168) | BL20 |
| 17 | Q (S) | 50S ribosomal protein L22 | polymer | 113 | 12481.6 | 1 | UniProt (P42060) Pfam (PF00237) | Bacillus subtilis (strain 168) | |
| 18 | R (T) | 50S ribosomal protein L23 | polymer | 95 | 10978.8 | 1 | UniProt (P42924) Pfam (PF00276) | Bacillus subtilis (strain 168) | |
| 19 | S (U) | 50S ribosomal protein L24 | polymer | 103 | 11166.1 | 1 | UniProt (P0CI78) Pfam (PF00467) Pfam (PF17136) | Bacillus subtilis (strain 168) | 12 kDa DNA-binding protein,BL23,HPB12 |
| 20 | T (W) | 50S ribosomal protein L27 | polymer | 94 | 10391.9 | 1 | UniProt (P05657) Pfam (PF01016) | Bacillus subtilis (strain 168) | BL24,BL30 |
| 21 | U (X) | 50S ribosomal protein L28 | polymer | 62 | 6826.1 | 1 | UniProt (P37807) Pfam (PF00830) | Bacillus subtilis (strain 168) | |
| 22 | V (Y) | 50S ribosomal protein L29 | polymer | 66 | 7728.0 | 1 | UniProt (P12873) Pfam (PF00831) | Bacillus subtilis (strain 168) | |
| 23 | W (Z) | 50S ribosomal protein L30 | polymer | 59 | 6650.8 | 1 | UniProt (P19947) Pfam (PF00327) | Bacillus subtilis (strain 168) | BL27 |
| 24 | X (0) | 50S ribosomal protein L32 | polymer | 59 | 6745.1 | 1 | UniProt (O34687) Pfam (PF01783) | Bacillus subtilis (strain 168) | |
| 25 | Y (1) | 50S ribosomal protein L33 1 | polymer | 49 | 5915.9 | 1 | UniProt (P56849) Pfam (PF00471) | Bacillus subtilis (strain 168) | |
| 26 | Z (2) | 50S ribosomal protein L34 | polymer | 44 | 5271.3 | 1 | UniProt (P05647) Pfam (PF00468) | Bacillus subtilis (strain 168) | |
| 27 | AA (3) | 50S ribosomal protein L35 | polymer | 66 | 7581.1 | 1 | UniProt (P55874) Pfam (PF01632) | Bacillus subtilis (strain 168) | |
| 28 | BA (4) | 50S ribosomal protein L36 | polymer | 37 | 4318.4 | 1 | UniProt (P20278) Pfam (PF00444) | Bacillus subtilis (strain 168) | BL38,Ribosomal protein B,Ribosomal protein II |
| 29 | CA (6) | 50S ribosomal protein L31 | polymer | 63 | 7159.2 | 1 | UniProt (Q03223) Pfam (PF01197) | Bacillus subtilis (strain 168) | |
| 30 | DA (7) | mRNA | polymer | 3 | 872.6 | 1 | Bacillus subtilis (strain 168) | ||
| 31 | EA (a) | 16S ribosomal RNA | polymer | 1554 | 503369.1 | 1 | GenBank (225184640) | Bacillus subtilis (strain 168) | |
| 32 | FA (b) | 30S ribosomal protein S2 | polymer | 246 | 28009.3 | 1 | UniProt (P21464) Pfam (PF00318) | Bacillus subtilis (strain 168) | BS1,Vegetative protein 209,VEG209 |
| 33 | GA (c) | 30S ribosomal protein S3 | polymer | 218 | 24364.9 | 1 | UniProt (P21465) Pfam (PF07650) Pfam (PF00189) | Bacillus subtilis (strain 168) | BS3,BS2 |
| 34 | HA (d) | 30S ribosomal protein S4 | polymer | 200 | 22874.3 | 1 | UniProt (P21466) Pfam (PF00163) Pfam (PF01479) | Bacillus subtilis (strain 168) | BS4 |
| 35 | IA (e) | 30S ribosomal protein S5 | polymer | 166 | 17650.6 | 1 | UniProt (P21467) Pfam (PF00333) Pfam (PF03719) | Bacillus subtilis (strain 168) | BS5 |
| 36 | JA (f) | 30S ribosomal protein S6 | polymer | 95 | 11140.5 | 1 | UniProt (P21468) Pfam (PF01250) | Bacillus subtilis (strain 168) | BS9 |
| 37 | KA (g) | 30S ribosomal protein S7 | polymer | 156 | 17915.9 | 1 | UniProt (P21469) Pfam (PF00177) | Bacillus subtilis (strain 168) | BS7 |
| 38 | LA (h) | 30S ribosomal protein S8 | polymer | 132 | 14901.4 | 1 | UniProt (P12879) Pfam (PF00410) | Bacillus subtilis (strain 168) | BS8 |
| 39 | MA (i) | 30S ribosomal protein S9 | polymer | 130 | 14335.5 | 1 | UniProt (P21470) Pfam (PF00380) | Bacillus subtilis (strain 168) | BS10 |
| 40 | NA (j) | 30S ribosomal protein S10 | polymer | 102 | 11687.7 | 1 | UniProt (P21471) Pfam (PF00338) | Bacillus subtilis (strain 168) | BS13 |
| 41 | OA (k) | 30S ribosomal protein S11 | polymer | 131 | 13952.0 | 1 | UniProt (P04969) Pfam (PF00411) | Bacillus subtilis (strain 168) | BS11 |
| 42 | PA (l) | 30S ribosomal protein S12 | polymer | 138 | 15248.7 | 1 | UniProt (P21472) Pfam (PF00164) | Bacillus subtilis (strain 168) | BS12 |
| 43 | QA (m) | 30S ribosomal protein S13 | polymer | 121 | 13818.1 | 1 | UniProt (P20282) Pfam (PF00416) | Bacillus subtilis (strain 168) | BS14 |
| 44 | RA (n) | 30S ribosomal protein S14 | polymer | 61 | 7263.8 | 1 | UniProt (P12878) Pfam (PF00253) | Bacillus subtilis (strain 168) | 30S ribosomal protein S14 type Z,30S ribosomal protein S14-1,BS-A |
| 45 | SA (o) | 30S ribosomal protein S15 | polymer | 89 | 10597.2 | 1 | UniProt (P21473) Pfam (PF00312) | Bacillus subtilis (strain 168) | BS18 |
| 46 | TA (p) | 30S ribosomal protein S16 | polymer | 90 | 10153.8 | 1 | UniProt (P21474) Pfam (PF00886) | Bacillus subtilis (strain 168) | BS17 |
| 47 | UA (q) | 30S ribosomal protein S17 | polymer | 87 | 10221.0 | 1 | UniProt (P12874) Pfam (PF00366) | Bacillus subtilis (strain 168) | BS16 |
| 48 | VA (r) | 30S ribosomal protein S18 | polymer | 79 | 8990.6 | 1 | UniProt (P21475) Pfam (PF01084) | Bacillus subtilis (strain 168) | BS21 |
| 49 | WA (s) | 30S ribosomal protein S19 | polymer | 92 | 10607.3 | 1 | UniProt (P21476) Pfam (PF00203) | Bacillus subtilis (strain 168) | BS19 |
| 50 | XA (t) | 30S ribosomal protein S20 | polymer | 88 | 9622.2 | 1 | UniProt (P21477) Pfam (PF01649) | Bacillus subtilis (strain 168) | BS20 |
| 51 | YA (x) | P-tRNA | polymer | 87 | 28094.6 | 1 | GenBank (1430654817) | Escherichia coli | |
| 52 | ZA (A) | TELITHROMYCIN | non-polymer | 812.0 | 1 | Chemie (TEL) PubChem (17753754) PubChem (22525209) PubChem (23958736) PubChem (16667730) PubChem (16760217) PubChem (21881641) PubChem (44317671) PubChem (44317862) PubChem (24847865) PubChem (25073503) PubChem (46783745) PubChem (56928074) PubChem (57885152) PubChem (58593562) PubChem (59907802) PubChem (58852891) PubChem (59842216) PubChem (70789201) PubChem (71752343) PubChem (5496803) PubChem (3002190) PubChem (73658) PubChem (71306735) PubChem (71296916) PubChem (443578) PubChem (73265197) PubChem (73440768) PubChem (9918852) PubChem (90660825) PubChem (91810863) PubChem (92043103) PubChem (5462516) PubChem (122130735) PubChem (124224913) PubChem (124746424) PubChem (124816457) PubChem (126480043) PubChem (129600749) PubChem (129600751) PubChem (129606930) PubChem (117072363) PubChem (11693521) PubChem (118701745) PubChem (122463193) PubChem (122505239) PubChem (124523680) PubChem (124746425) PubChem (138402871) PubChem (129600750) PubChem (129600752) PubChem (134695314) PubChem (138107029) PubChem (166639598) PubChem (140815520) PubChem (173721432) PubChem (165712195) PubChem (168322563) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 51 |
| Total formula weight | 2136280.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 812.0 | |
| All* | Total formula weight | 2137092.7 |
