6H6U
Unitary crystal structure of the positively supercharged variant Ftn(pos) from human heavy chain ferritin (PEG 400 condition)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ferritin heavy chain | polymer | 183 | 21499.2 | 6 | UniProt (P02794) Pfam (PF00210) | Homo sapiens (Human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein |
| 2 | G, H, I, K, L... (A, B, C, D, E...) | FE (III) ION | non-polymer | 55.8 | 15 | Chemie (FE) | |||
| 3 | J (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | N, Q, T, U (B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | AA, BA, CA, DA, EA... (A, B, C, D, E...) | water | water | 18.0 | 89 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 0 - 182 (UniProt: P02794)
| PDB | External Database | Details |
|---|---|---|
| Lys 18 | Ala 19 | engineered mutation |
| Arg 25 | Asn 26 | engineered mutation |
| Gln 86 | Lys 87 | engineered mutation |
| Lys 90 | Cys 91 | engineered mutation |
| Arg 98 | Asn 99 | engineered mutation |
| Lys 102 | Cys 103 | engineered mutation |
| Lys 105 | His 106 | engineered mutation |
| Lys 109 | Asn 110 | engineered mutation |
| Lys 123 | Asp 124 | engineered mutation |
| Arg 162 | Glu 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 128995.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 1090.1 | |
| All* | Total formula weight | 130085.6 |
