6H6U

Unitary crystal structure of the positively supercharged variant Ftn(pos) from human heavy chain ferritin (PEG 400 condition)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Ferritin heavy chain	polymer	183	21499.2	6	UniProt (P02794) Pfam (PF00210) In PDB	Homo sapiens (Human)	Ferritin H subunit,Cell proliferation-inducing gene 15 protein
2	A, B, C, D, E...	FE (III) ION	non-polymer		55.8	15	Chemie (FE)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	B, C, D	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
5		water	water		18.0	89	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 0 - 182 (UniProt: P02794)

PDB	External Database	Details
Lys 18	Ala 19	engineered mutation
Arg 25	Asn 26	engineered mutation
Gln 86	Lys 87	engineered mutation
Lys 90	Cys 91	engineered mutation
Arg 98	Asn 99	engineered mutation
Lys 102	Cys 103	engineered mutation
Lys 105	His 106	engineered mutation
Lys 109	Asn 110	engineered mutation
Lys 123	Asp 124	engineered mutation
Arg 162	Glu 163	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	128995.5
Non-Polymers*	Number of molecules	20
	Total formula weight	1090.1
All*	Total formula weight	130085.6

*Water molecules are not included.