6H6K
The structure of the FKR mutant of the archaeal translation initiation factor 2 gamma subunit in complex with GDPCP, obtained in the absence of magnesium salts in the crystallization solution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Translation initiation factor 2 subunit gamma | polymer | 415 | 45628.9 | 5 | UniProt (Q980A5) Pfam (PF00009) Pfam (PF09173) | Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) | aIF2-gamma,eIF-2-gamma |
| 2 | F, J, N, R, T (A, B, C, D, E) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 5 | Chemie (GCP) | |||
| 3 | G, H, I, K, L... (A, B) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 4 | O, P, Q, S (C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | U, V, W, X, Y (A, B, C, D, E) | water | water | 18.0 | 831 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 415 (UniProt: Q980A5)
| PDB | External Database | Details |
|---|---|---|
| Ala 221 | Phe 221 | engineered mutation |
| Ala 225 | Lys 225 | engineered mutation |
| Ala 280 | Arg 280 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 228144.6 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2992.3 | |
| All* | Total formula weight | 231136.8 |
