6H4G
Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Protein kinase A regulatory subunit | polymer | 301 | 34383.0 | 2 | UniProt (Q385V6) Pfam (PF00027) In PDB | Trypanosoma brucei brucei TREU927 | |
2 | A, B | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) | |||
3 | A, B | INOSINE | non-polymer | 268.2 | 2 | Chemie (NOS) | |||
4 | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A, B: 199 - 499 (UniProt: Q385V6)
PDB | External Database | Details |
---|---|---|
Ala 311 | Glu 311 | engineered mutation |
Arg 318 | Thr 318 | engineered mutation |
Ala 319 | Val 319 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 68766.1 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1194.9 | |
All* | Total formula weight | 69960.9 |