6H4G
Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein kinase A regulatory subunit | polymer | 301 | 34383.0 | 2 | UniProt (Q385V6) Pfam (PF00027) | Trypanosoma brucei brucei TREU927 | |
| 2 | C, E (A, B) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) | |||
| 3 | D, F (A, B) | INOSINE | non-polymer | 268.2 | 2 | Chemie (NOS) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 320 | Chemie (HOH) |
Sequence modifications
A, B: 199 - 499 (UniProt: Q385V6)
| PDB | External Database | Details |
|---|---|---|
| Ala 311 | Glu 311 | engineered mutation |
| Arg 318 | Thr 318 | engineered mutation |
| Ala 319 | Val 319 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68766.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1194.9 | |
| All* | Total formula weight | 69960.9 |
