6H45
crystal structure of the human TGT catalytic subunit QTRT1 in complex with queuine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Queuine tRNA-ribosyltransferase catalytic subunit 1 | polymer | 392 | 43114.5 | 2 | UniProt (Q9BXR0) Pfam (PF01702) | Homo sapiens (human) | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 2 | C, K (A, B) | 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one | non-polymer | 277.3 | 2 | Chemie (QEI) | |||
| 3 | D, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, I, M, R (A, B) | BROMIDE ION | non-polymer | 79.9 | 4 | Chemie (BR) | |||
| 5 | F, G, J, O, P (A, B) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | H, Q (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 7 | N (B) | GLUTAMIC ACID | non-polymer | 147.1 | 1 | Chemie (GLU) | |||
| 8 | S, T (A, B) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86228.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1407.6 | |
| All* | Total formula weight | 87636.5 |
