6H27

Structure of S70C BlaC from Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	BlaC	polymer	274	29491.1	2	UniProt (P0A5I7) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3)	Mycobacterium tuberculosis
2	C (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
3	D, E (A, B)	2-(2-METHOXYETHOXY)ETHANOL	non-polymer		120.1	2	Chemie (PG0)
4	F, G (A, B)	water	water		18.0	145	Chemie (HOH)

Sequence modifications

A, B: 29 - 293 (UniProt: P0A5I7)

PDB	External Database	Details
Met 28	-	initiating methionine
Cys 70	Ser 84	engineered mutation
Leu 294	-	expression tag
Glu 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
His 299	-	expression tag
His 300	-	expression tag
His 301	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	58982.2
Non-Polymers*	Number of molecules	3
	Total formula weight	302.4
All*	Total formula weight	59284.6

*Water molecules are not included.