6H1I
Crystal structure of human Pirin in complex with bisamide compound 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Pirin | polymer | 293 | 32441.7 | 1 | UniProt (O00625) Pfam (PF02678) Pfam (PF05726) | Homo sapiens (Human) | Probable quercetin 2,3-dioxygenase PIR,Probable quercetinase |
| 2 | B (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 3 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F (A) | ~{N}-[5-(2,3-dihydro-1,4-benzodioxin-6-ylcarbonylamino)-2-methyl-phenyl]-2-methyl-quinoline-6-carboxamide | non-polymer | 453.5 | 1 | Chemie (FJH) | |||
| 5 | G (A) | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
A: 1 - 290 (UniProt: O00625)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32441.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 785.6 | |
| All* | Total formula weight | 33227.3 |
