6H1F
Structure of the nanobody-stabilized gelsolin D187N variant (second domain)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | gelsolin nanobody, Nb11 | polymer | 140 | 15266.8 | 1 | Lama glama (llama) | ||
| 2 | B | Gelsolin | polymer | 119 | 13165.7 | 1 | UniProt (P06396) Pfam (PF00626) In PDB | Homo sapiens (Human) | AGEL,Actin-depolymerizing factor,ADF,Brevin |
| 3 | A | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 4 | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
B: 151 - 266 (UniProt: P06396)
| PDB | External Database | Details |
|---|---|---|
| Gly 148 | - | expression tag |
| Ser 149 | - | expression tag |
| His 150 | - | expression tag |
| Asn 187 | Asp 214 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28432.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 58.1 | |
| All* | Total formula weight | 28490.5 |
