6H0S
Crystal structure of the complex between the Lactococcus lactis FPG mutant G226P and a Fapy-dG containing DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Formamidopyrimidine-DNA glycosylase | polymer | 271 | 31156.3 | 1 | UniProt (A0A165FVI1) Pfam (PF01149) Pfam (PF06831) Pfam (PF06827) UniProt (by SIFTS) (P42371) | Lactococcus lactis subsp. cremoris | Fapy-DNA glycosylase,DNA-(apurinic or apyrimidinic site) lyase MutM,AP lyase MutM |
| 2 | B (B) | DNA (5'-D(*CP*TP*CP*TP*TP*TP*(FOX)P*TP*TP*TP*CP*TP*CP*G)-3') | polymer | 14 | 4219.8 | 1 | synthetic construct | ||
| 3 | C (C) | DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3') | polymer | 14 | 4355.9 | 1 | synthetic construct | ||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F, G, H (A, B, C) | water | water | 18.0 | 422 | Chemie (HOH) |
Sequence modifications
A: 1 - 271 (UniProt: A0A165FVI1)
| PDB | External Database | Details |
|---|---|---|
| Pro 226 | Gly 227 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 39731.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 157.5 | |
| All* | Total formula weight | 39889.4 |
