Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003677 | molecular_function | DNA binding |
A | 0003684 | molecular_function | damaged DNA binding |
A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
A | 0006281 | biological_process | DNA repair |
A | 0006284 | biological_process | base-excision repair |
A | 0008270 | molecular_function | zinc ion binding |
A | 0008534 | molecular_function | oxidized purine nucleobase lesion DNA N-glycosylase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
A | 0016829 | molecular_function | lyase activity |
A | 0019104 | molecular_function | DNA N-glycosylase activity |
A | 0034039 | molecular_function | 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue ZN A 5001 |
Chain | Residue |
A | CYS245 |
A | CYS248 |
A | CYS265 |
A | CYS268 |
site_id | AC2 |
Number of Residues | 10 |
Details | binding site for residue GOL A 5002 |
Chain | Residue |
A | TYR125 |
A | LYS129 |
A | HOH5189 |
B | DT9 |
B | DT10 |
A | TYR58 |
A | HIS72 |
A | ARG74 |
A | THR113 |
A | GLU115 |
Functional Information from PROSITE/UniProt
site_id | PS01242 |
Number of Residues | 25 |
Details | ZF_FPG_1 Zinc finger FPG-type signature. Csr..CGaeIqkikvag....RGthFCpvCQ |
Chain | Residue | Details |
A | CYS245-GLN269 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 34 |
Details | ZN_FING: FPG-type |
Chain | Residue | Details |
A | VAL237-LYS271 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | ACT_SITE: Schiff-base intermediate with DNA => ECO:0000305 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor => ECO:0000305 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor; for beta-elimination activity => ECO:0000305 |
Chain | Residue | Details |
A | LYS57 | |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | ACT_SITE: Proton donor; for delta-elimination activity => ECO:0000305 |
Chain | Residue | Details |
A | GLY261 | |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
A | HIS91 | |
A | ARG109 | |